Colohan Shannon M
Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.
J Burn Care Res. 2010 Jul-Aug;31(4):529-39. doi: 10.1097/BCR.0b013e3181e4d680.
Burn injuries are a significant problem with high associated morbidity and mortality. Those associated with inhalational trauma (IHT) may be associated with higher mortality, but studies on prognosis are small and underpowered. This study was designed to identify prognostic factors that increase the risk of death, to quantify this risk, and to identify existing prognostic models. An electronic search of English-language publications that identify prognostic risk factors in thermal burns including IHT was carried out. Each article was reviewed systematically, and data extraction, quality assessment, and summarization of the articles were performed. Thirteen articles that met the inclusion/exclusion criteria of this study were reviewed. Overall, the mortality rate among burn patients in this review was 13.9% (4-28.3%), with the mortality rate among those with IHT being 27.6% (7.8-28.3%). Those studies with multivariate analyses identified increasing %TBSA, presence of IHT, and increasing age as the strongest predictors for mortality in this patient population. It seems that %TBSA, presence of IHT, and age are the best predictors of mortality among the current published literature on burn prognosis.
烧伤是一个严重的问题，具有较高的发病率和死亡率。那些伴有吸入性创伤（IHT）的烧伤可能与更高的死亡率相关，但关于预后的研究规模较小且效能不足。本研究旨在确定增加死亡风险的预后因素，量化这种风险，并识别现有的预后模型。对识别包括IHT在内的热烧伤预后风险因素的英文出版物进行了电子检索。对每篇文章进行了系统综述，并进行了数据提取、质量评估和文章总结。对13篇符合本研究纳入/排除标准的文章进行了综述。总体而言，本综述中烧伤患者的死亡率为13.9%（4%-28.3%），伴有IHT的患者死亡率为27.6%（7.8%-28.3%）。那些进行多变量分析的研究确定，烧伤总面积（%TBSA）增加、存在IHT以及年龄增长是该患者群体死亡率的最强预测因素。在目前已发表的关于烧伤预后的文献中，%TBSA、IHT的存在和年龄似乎是死亡率的最佳预测因素。
