Department of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
Ophthalmic Plast Reconstr Surg. 2010 Jul-Aug;26(4):295-7. doi: 10.1097/IOP.0b013e3181c0929a.
A 41-year-old woman presented with pyoderma gangrenosum involving the right eyelids. Over the course of 3 years, she developed progressive scarring of the eyelids with lagophthalmos and corneal exposure. Multiple reconstructive procedures were performed with varying degrees of success. Despite aggressive medical control of her disease, it recurred in grafted skin on her upper and lower eyelids as confirmed by tissue biopsy. Periocular pyoderma gangrenosum is a rare disease where the management may be complicated by disease recurrence in reconstructed tissues, including skin grafts as this case demonstrates.
一位 41 岁女性因患有脓性皮肤溃疡而出现右眼睑受累。在 3 年的时间里，她的眼睑逐渐出现瘢痕化、眼睑闭合不全和角膜暴露。尽管进行了多次重建手术，但效果各不相同。尽管积极控制疾病，但在她的上下眼睑移植皮肤上仍出现复发，组织活检证实了这一点。眼部脓性皮肤溃疡是一种罕见疾病，其管理可能因包括皮肤移植在内的重建组织中疾病复发而变得复杂，正如本例所示。
