School of Education, Faculty of Education and Arts, University of Newcastle, Callaghan, New South Wales, Australia.
Obesity (Silver Spring). 2011 Jan;19(1):142-51. doi: 10.1038/oby.2010.119. Epub 2010 Jun 3.
This article reports the 12-month follow-up results and process evaluation of the SHED-IT (Self-Help, Exercise, and Diet using Information Technology) trial, an Internet-based weight loss program exclusively for men. Sixty-five overweight/obese male staff and students at the University of Newcastle (Callaghan, Australia) (mean (s.d.) age = 35.9 (11.1) years; BMI = 30.6 (2.8)) were randomly assigned to either (i) Internet group (n = 34) or (ii) Information only control group (n = 31). Both received one face-to-face information session and a program booklet. Internet group participants were instructed to use the study website for 3 months. Participants were assessed at baseline, 3-, 6-, and 12-month follow-up for weight, waist circumference, BMI, blood pressure, and resting heart rate. Retention at 3- and 12-months was 85% and 71%, respectively. Intention-to-treat (ITT) analysis using linear mixed models revealed significant and sustained weight loss of -5.3 kg (95% confidence interval (CI): -7.5, -3.0) at 12 months for the Internet group and -3.1 kg (95% CI: -5.4, -0.7) for the control group with no group difference. A significant time effect was found for all outcomes (P < 0.001). Per-protocol analysis revealed a significant group-by-time interaction for weight, waist circumference, BMI, and systolic blood pressure. Internet group compliers (who self-monitored as instructed) maintained greater weight loss at 12 months (-8.8 kg; 95% CI -11.8, -5.9) than noncompliers (-1.9 kg; 95% CI -4.8, 1.0) and controls (-3.0 kg; 95% CI -5.2, -0.9). Qualitative analysis by questionnaire and interview highlighted the acceptability and satisfaction with SHED-IT. Low-dose approaches to weight loss are feasible, acceptable, and can achieve clinically important weight loss in men after 1-year follow-up.
这篇文章报告了 SHED-IT（使用信息技术进行自助、锻炼和饮食）试验的 12 个月随访结果和过程评估，这是一个专门针对男性的基于互联网的减肥计划。65 名超重/肥胖的纽卡斯尔大学（卡利加尔）男性员工和学生（平均（标准差）年龄=35.9（11.1）岁；BMI=30.6（2.8））被随机分配到以下两组：（i）互联网组（n=34）或（ii）信息仅对照组（n=31）。两组都接受了一次面对面的信息会议和一本计划手册。互联网组参与者被指导在研究网站上使用 3 个月。参与者在基线、3 个月、6 个月和 12 个月时接受体重、腰围、BMI、血压和静息心率的评估。3 个月和 12 个月的保留率分别为 85%和 71%。使用线性混合模型进行意向治疗（ITT）分析显示，互联网组在 12 个月时体重显著且持续减轻 5.3 公斤（95%置信区间（CI）：-7.5，-3.0），对照组减轻 3.1 公斤（95%CI：-5.4，-0.7），两组之间没有差异。所有结果都发现有显著的时间效应（P < 0.001）。按方案分析显示，体重、腰围、BMI 和收缩压的组间时间交互作用显著。互联网组遵守者（按指示自我监测）在 12 个月时保持了更大的体重减轻（-8.8 公斤；95%CI -11.8，-5.9），而不遵守者（-1.9 公斤；95%CI -4.8，1.0）和对照组（-3.0 公斤；95%CI -5.2，-0.9）。通过问卷和访谈进行的定性分析突出了 SHED-IT 的可接受性和满意度。低剂量的减肥方法是可行的、可接受的，并且可以在 1 年随访后使男性实现临床重要的体重减轻。
