Am J Gastroenterol. 2010 Jun;105(6):1298-300. doi: 10.1038/ajg.2009.739.
Recent publications assessing colonoscopy missed rates of colorectal cancer have generated efforts toward colonoscopy quality improvement. To date, esophagogastroduodenoscopy (EGD) has escaped similar scrutiny in Western populations. Raftopoulos et al. (1) report an upper gastrointestinal cancer missed rate of up to 6.7% in a cohort of 28,000 patients who underwent EGD at a hospital-based endoscopy unit in Perth, Western Australia. Of the missed esophageal and gastric cancers, approximately 80% of patients had alarm symptoms and 73% had abnormalities reported at the time of EGD. The missed cancers may not have been visualized, or were visualized and either not biopsied or biopsied inadequately, or interpreted incorrectly by pathologists. There was no difference in survival between the missed cancers and those detected at the index EGD.
最近发表的评估结直肠癌症结肠镜检查遗漏率的文献，促使人们努力提高结肠镜检查的质量。迄今为止，在西方人群中，上消化道内镜检查（EGD）尚未受到类似的审查。Raftopoulos 等人（1）报告了在西澳大利亚珀斯一家医院内镜检查中心接受 EGD 的 28000 名患者中，上消化道癌症的漏诊率高达 6.7%。在漏诊的食管癌和胃癌中，约 80%的患者有报警症状，73%的患者在 EGD 时报告有异常。漏诊的癌症可能未被观察到，或者被观察到但未进行活检或活检不充分，或者病理学家的解释不正确。在生存方面，漏诊癌症与在指数 EGD 中检测到的癌症之间没有差异。
