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使用义眼诱发双侧木质性结膜炎。

Induction of bilateral ligneous conjunctivitis with the use of a prosthetic eye.

作者信息

Yazıcı Bülent, Yıldız Meral, Irfan Tayfun

机构信息

Department of Ophthalmology, Uludag University, 16059, Bursa, Turkey.

出版信息

Int Ophthalmol. 2011 Feb;31(1):25-8. doi: 10.1007/s10792-010-9381-0. Epub 2010 Jun 4.

DOI:10.1007/s10792-010-9381-0
PMID:20524141
Abstract

The purpose of this article to report a case of ligneous conjunctivitis in an anophthalmic socket, in respect of a 20-year-old woman. The subject woman had a history of left enucleation surgery presented with bilateral palpebral ligneous conjunctivitis and ligneous gingivitis. The hematologic study revealed a severe plasma plasminogen deficiency. The eyelid lesions were successfully treated with surgical excision, topical heparin and corticosteroid eyedrops. However, the ligneous lesions recurred bilaterally after she was fitted with a prosthetic eye and were refractory to intensive topical treatment with heparin and cyclosporin A eye drops. This case shows that the use of a prosthetic eye may induce ligneous conjunctivitis in an anophthalmic socket and normal eye which is refractory to topical treatment.

摘要

本文旨在报告一例无眼球眼眶的木质化性结膜炎病例,患者为一名20岁女性。该女性有左眼眼球摘除手术史,出现双侧睑部木质化性结膜炎和木质化性牙龈炎。血液学研究显示严重的血浆纤溶酶原缺乏。眼睑病变通过手术切除、局部应用肝素和皮质类固醇滴眼液成功治疗。然而,在她佩戴义眼后,双侧木质化病变复发,对肝素和环孢素A滴眼液的强化局部治疗无效。该病例表明,佩戴义眼可能会在无眼球眼眶和正常眼中诱发木质化性结膜炎,且局部治疗无效。

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Long-term follow-up in a pediatric patient with Ligneous Conjunctivitis due to PLG gene mutation in topical plasminogen treatment after successful use of ocular prosthesis for aesthetic rehabilitation: a case report.局部应用纤溶酶原治疗 PLG 基因突变导致的儿童板层状结膜炎后的长期随访:病例报告。
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本文引用的文献

1
The first two Japanese cases of severe type I congenital plasminogen deficiency with ligneous conjunctivitis: successful treatment with direct thrombin inhibitor and fresh plasma.日本首例两例伴有木样结膜炎的严重I型先天性纤溶酶原缺乏症:直接凝血酶抑制剂和新鲜血浆治疗成功
Am J Hematol. 2009 Jun;84(6):363-5. doi: 10.1002/ajh.21402.
2
Successful treatment of ligneous gingivitis with warfarin.华法林成功治疗木样牙龈炎。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Jan;107(1):77-80. doi: 10.1016/j.tripleo.2008.08.007. Epub 2008 Nov 8.
3
Hypoplasminogenemia with ligneous periodontitis: a failed local therapeutic approach.
低纤溶酶原血症合并纤维蛋白性牙周炎:一种失败的局部治疗方法。
J Periodontol. 2007 Jun;78(6):1164-75. doi: 10.1902/jop.2007.060422.
4
Clinical manifestations due to severe plasminogen deficiency: a case report.严重纤溶酶原缺乏所致临床表现:一例报告
J Dent Child (Chic). 2006 Sep-Dec;73(3):179-82.
5
Prevention of ligneous conjunctivitis by topical and subconjunctival fresh frozen plasma.局部及结膜下应用新鲜冷冻血浆预防木样结膜炎
Am J Ophthalmol. 2004 Aug;138(2):299-300. doi: 10.1016/j.ajo.2004.02.067.
6
Contraceptive pills induce an improvement in congenital hypoplasminogenemia in two unrelated patients with ligneous conjunctivitis.避孕药使两名患有木质化结膜炎的非亲属患者的先天性低纤溶酶原血症得到改善。
Thromb Haemost. 2003 Jul;90(1):86-91.
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Ligneous conjunctivitis.木样结膜炎
Surv Ophthalmol. 2003 Jul-Aug;48(4):369-88. doi: 10.1016/s0039-6257(03)00056-0.
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Effective treatment of ligneous conjunctivitis with topical plasminogen.局部应用纤溶酶原有效治疗木样结膜炎。
Am J Ophthalmol. 2002 Apr;133(4):451-5. doi: 10.1016/s0002-9394(01)01433-7.
9
Homozygous type I plasminogen deficiency.纯合子I型纤溶酶原缺乏症。
Semin Thromb Hemost. 1997;23(3):259-69. doi: 10.1055/s-2007-996099.
10
Topical heparin in the treatment of ligneous conjunctivitis.局部应用肝素治疗木样结膜炎。
Ophthalmology. 1995 Nov;102(11):1654-9. doi: 10.1016/s0161-6420(95)30813-5.