低纤溶酶原血症合并纤维蛋白性牙周炎：一种失败的局部治疗方法。
Hypoplasminogenemia with ligneous periodontitis: a failed local therapeutic approach.
作者信息
Kurtulus Idil, Gokbuget Aslan, Efeoglu Ahmet, Cintan Serdar, Tefs Katrin, Schuster Volker, Scully Crispian
机构信息
Department of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
出版信息
J Periodontol. 2007 Jun;78(6):1164-75. doi: 10.1902/jop.2007.060422.
BACKGROUND
Hypoplasminogenemia is a rare condition that is associated with ligneous conjunctivitis, a form of chronic conjunctivitis characterized by firm, fibrin-rich, pseudomembranous lesions on the tarsal conjunctivae and oral lesions. Pseudomembranes may develop on the gingivae, and there may be periodontal involvement.
METHODS
Several therapeutic approaches have been developed to treat such patients, but they have had limited effect. We used gingivectomies, topical heparin, and corticosteroids to treat periodontal lesions in an 18-year-old girl.
RESULTS
This approach had no benefit.
CONCLUSION
The question remains about how best to manage patients with hypoplasminogenemia.
背景
低纤溶酶原血症是一种罕见病症，与木样结膜炎相关，木样结膜炎是慢性结膜炎的一种形式，其特征为睑结膜出现坚实、富含纤维蛋白的假膜性病变以及口腔病变。假膜可能出现在牙龈上，且可能存在牙周受累情况。
方法
已开发出多种治疗方法来治疗此类患者，但效果有限。我们采用牙龈切除术、局部应用肝素和皮质类固醇来治疗一名18岁女孩的牙周病变。
结果
该方法并无益处。
结论
如何最佳地管理低纤溶酶原血症患者的问题依然存在。
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