Dash Suvakanta, Murthy Padala Narasimha, Nath Lilakanta, Chowdhury Prasanta
Girijananda Chowdhury Institute of Pharmaceutical Science, Azara, Hathkhowapara, NH-37, Guwahati, Assam 781 017, India.
Acta Pol Pharm. 2010 May-Jun;67(3):217-23.
In this paper we review the mathematical models used to determine the kinetics of drug release from drug delivery systems. The quantitative analysis of the values obtained in dissolution/release rates is easier when mathematical formulae are used to describe the process. The mathematical modeling can ultimately help to optimize the design of a therapeutic device to yield information on the efficacy of various release models.
在本文中,我们回顾了用于确定药物从给药系统释放动力学的数学模型。当使用数学公式来描述溶解/释放速率过程时,对所获得值的定量分析会更容易。数学建模最终有助于优化治疗装置的设计,以获取有关各种释放模型功效的信息。