Department of Dermatology, Gloucester Royal Hospital, Gloucester, UK.
Drugs Aging. 2010 Jun 1;27(6):451-6. doi: 10.2165/11315930-000000000-00000.
Chronic actinic dermatitis (CAD) describes a condition resulting from abnormal photosensitivity; the dermatitis is clinically similar to contact allergic dermatitis. Sun-exposed skin is more commonly affected but the condition can extend to and encompass unexposed skin. CAD is relatively rare but becomes more prevalent in the elderly population. Phototesting, patch testing and laboratory results should be used to help guide diagnosis. In the elderly, it is important to distinguish CAD from drug-induced photosensitivity. Management of the condition requires sunlight avoidance and use of sunscreens, topical emollients and topical corticosteroids. Oral corticosteroids and immunosuppressive therapy such as azathioprine may be indicated but should be used with caution in the elderly.
慢性光化性皮炎（CAD）描述的是一种由异常光敏感性引起的病症；其临床表现与接触过敏性皮炎相似。受阳光照射的皮肤更容易受到影响，但病情也可能会扩展到未暴露的皮肤。CAD 相对较为罕见，但在老年人群中更为常见。光测试、斑贴试验和实验室结果可用于辅助诊断。在老年人中，重要的是要将 CAD 与药物诱导的光敏感性区分开来。该病症的治疗需要避免阳光照射并使用防晒霜、局部保湿剂和局部皮质类固醇。口服皮质类固醇和免疫抑制疗法，如硫唑嘌呤，可能是必要的，但在老年人中应谨慎使用。
