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趾骨小细胞骨肉瘤:一例报告并文献复习

Small cell osteosarcoma of a toe phalanx: a case report and review of literature.

作者信息

Posthumadeboer Jantine, Graat Harm Ca, Bras Johannes, Saouti Rachid

机构信息

Department of Orthopaedic Surgery, VU University Medical Centre, Amsterdam,, The Netherlands.

出版信息

J Orthop Surg Res. 2010 Jun 3;5:36. doi: 10.1186/1749-799X-5-36.

Abstract

This report describes the radiological and histological findings of a small cell osteosarcoma of a toe phalanx in a 38 year old man. This man presented with pain, swelling and redness of the left third toe. Medical history revealed an osteomyelitis of this toe eight years prior. Based on clinical findings and medical history the lesion was diagnosed as an osteomyelitis. However, peroperatively the lesion had a malignant aspect. Histological examination revealed a small cell osteosarcoma of the proximal phalanx.Osteosarcoma of the foot and especially of the tubular bones is rare. Moreover small cell osteosarcoma is a rare subtype of osteosarcoma. This case demonstrates that medical history and clinical examination can be misleading. In patients with apparent bone destruction, a malignancy must always be excluded prior to treatment. It emphasises the care that should be taken in the process of formulating a diagnosis.

摘要

本报告描述了一名38岁男性趾骨小细胞骨肉瘤的放射学和组织学检查结果。该男子表现为左足第三趾疼痛、肿胀和发红。病史显示该趾八年前曾患骨髓炎。基于临床检查结果和病史,该病变被诊断为骨髓炎。然而,手术中该病变具有恶性特征。组织学检查显示近端趾骨为小细胞骨肉瘤。足部骨肉瘤,尤其是管状骨骨肉瘤较为罕见。此外,小细胞骨肉瘤是骨肉瘤的一种罕见亚型。本病例表明病史和临床检查可能会产生误导。对于有明显骨质破坏的患者,在治疗前必须始终排除恶性肿瘤。它强调了在诊断过程中应谨慎行事。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4da/2892445/bb8f5db78b13/1749-799X-5-36-1.jpg

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