NEST, Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, I-56127 Pisa, Italy.
Lab Chip. 2010 Aug 7;10(15):1997-2000. doi: 10.1039/c000490a. Epub 2010 Jun 7.
Fully controlled liquid injection and flow in hydrophobic polydimethylsiloxane (PDMS) two-dimensional microchannel arrays based on on-chip integrated, low-voltage-driven micropumps are demonstrated. Our architecture exploits the surface-acoustic-wave (SAW) induced counterflow mechanism and the effect of nebulization anisotropies at crossing areas owing to lateral propagating SAWs. We show that by selectively exciting single or multiple SAWs, fluids can be drawn from their reservoirs and moved towards selected positions of a microchannel grid. Splitting of the main liquid flow is also demonstrated by exploiting multiple SAW beams. As a demonstrator, we show simultaneous filling of two orthogonal microchannels. The present results show that SAW micropumps are good candidates for truly integrated on-chip fluidic networks allowing liquid control in arbitrarily shaped two-dimensional microchannel arrays.
基于芯片集成的低压驱动微泵，实现了完全可控的液体注入和在疏水性聚二甲基硅氧烷（PDMS）二维微通道阵列中的流动。我们的架构利用了表面声波（SAW）诱导的逆流机制，以及横向传播的 SAW 在交叉区域雾化各向异性的影响。我们表明，通过选择性地激励单个或多个 SAW，可以将流体从其储液器中抽出并移动到微通道网格的选定位置。通过利用多个 SAW 光束，还可以实现主液体流的分裂。作为演示，我们展示了同时填充两个正交微通道的情况。目前的结果表明，SAW 微泵是真正集成的芯片上流体网络的理想选择，允许在任意形状的二维微通道阵列中控制液体。
