Faghihi Gita, Vali Anahita, Radan Mohammadreza, Eslamieh Golamreza, Tajammoli Shadi
Department of Dermatology, Isfahan University of Medical Sciences, Alzahra Hospital, Isfahan, Iran.
Skinmed. 2010 Mar-Apr;8(2):70-1.
Viral warts are a common problem especially in young people. They are an important topic as they are transmittable and cause social embarrassment. Though there are several treatments for viral warts, none offer a fast, simple, complete cure by itself. A simple and inexpensive way of treatment would be outstanding, especially in the developing countries. The authors' goal was to determine in patients with warts, the efficacy and safety of topical puncture with 85% formic acid in distilled water solution. A placebo-controlled, clinical trial was performed in patients with common viral warts who were referred to the Khorshid and Beheshti dermatology centers of Isfahan Medical School in 2003 and 2004. A total of 34 patients received 85% formic acid in distilled water solution on their lesion on one side of the body and distilled water as placebo on the other side of the body, every other day, using a needle puncture technique. Follow-up occurred every 2 weeks up to 3 months for all patients. Ninety-one percent of patients who received formic acid application showed complete disappearance of warts after follow-up period, compared to 10% in the placebo (distilled water) group. The results show that the application of 85% formic acid in distilled water solution is a safe and effective treatment for common warts with few side effects and good compliance.
病毒性疣是一个常见问题，尤其在年轻人中。它们是一个重要话题，因为具有传染性且会造成社交尴尬。尽管有多种治疗病毒性疣的方法，但没有一种能单独提供快速、简单、彻底的治愈方案。一种简单且廉价的治疗方法将会非常出色，特别是在发展中国家。作者的目标是确定在疣患者中，85%甲酸蒸馏水溶剂局部穿刺的疗效和安全性。2003年和2004年，在被转诊至伊斯法罕医科大学科尔希德和贝赫什提皮肤科中心的普通病毒性疣患者中进行了一项安慰剂对照临床试验。共有34名患者采用针刺技术，每隔一天在身体一侧的病损处涂抹85%甲酸蒸馏水溶剂，在身体另一侧涂抹蒸馏水作为安慰剂。所有患者每2周进行一次随访，持续3个月。随访期后，接受甲酸治疗的患者中有91%的疣完全消失，而安慰剂（蒸馏水）组为10%。结果表明，85%甲酸蒸馏水溶剂治疗普通疣安全有效，副作用少且依从性好。
