Samolis S, Panagopoulos P, Kanellopoulos N, Papastefanou I, Karadaglis S, Katsoulis M
Department of Obstetrics & Gynaecology, Tzaneio General Hospital, Pireaus, Greece.
Eur J Gynaecol Oncol. 2010;31(2):233-4.
Primary malignant vaginal melanoma is a rare vaginal tumour accompanied by an extremely high risk of local recurrence, distant metastasis and a small survival rate. Due to the fact that vaginal melanoma is quite uncommon there is lack of powerful prospective studies in the literature, thus the treatment choice remains controversial. An 85-year-old woman with a primary malignant vaginal melanoma located on the left lateral aspect of the distal vagina, with the greatest diameter almost 5 cm, was referred to our clinic. There was not any sign of local or distant metastasis identified. According to the most recently published data in the international literature, we decided along with the patient to perform conservative dissection of the tumor with free surgical margins as the appropriate mode of therapy. Radiotherapy, chemotherapy or radical extirpation cannot increase the survival time, even if there is a local or distant spread of melanoma.
原发性恶性阴道黑色素瘤是一种罕见的阴道肿瘤，局部复发、远处转移风险极高，生存率低。由于阴道黑色素瘤相当罕见，文献中缺乏有力的前瞻性研究，因此治疗选择仍存在争议。一名85岁女性，原发性恶性阴道黑色素瘤位于阴道远端左侧，最大直径近5厘米，被转诊至我院。未发现任何局部或远处转移迹象。根据国际文献中最新发表的数据，我们与患者决定，以手术切缘阴性的肿瘤保守切除术作为合适的治疗方式。即使黑色素瘤出现局部或远处扩散，放疗、化疗或根治性切除也无法延长生存时间。
