Bukhari Uzma, Sadiq Saleem, Memon Jawaid Hussin, Baig Farooq
Pathology Department, Muhammad Medical College, Mirpurkhas.
J Pak Med Assoc. 2010 May;60(5):365-7.
To evaluate the frequency and types of thyroid carcinoma with respect to age and sex groups.
This was a retrospective study conducted at the Department of Pathology, Basic Medical Sciences Institute, Jinnah postgraduate medical centre Karachi. A total of 998 thyroid lesions over a period of 05 years, from July 2000 to June 2005 were reviewed. H and E slides were studied to determine the types and frequencies of malignant lesions of thyroid. Special stains were performed whenever required.
A total of 998 thyroid lesions were reviewed, of which 153 were found to be malignant. Papillary carcinoma was the commonest malignant lesion with a frequency of 90.2% followed by 4.5% medullary carcinoma, 2% follicular carcinoma, 2% undifferentiated carcinoma and 0.7% each of mixed medullary and papillary carcinoma and poorly differentiated carcinoma. Females were predominant 82.4% as compared to males 17.6% with female to male ratio 4.7:1. Maximum number of the patients were seen in 4th decade of life followed by 3rd and 2nd decades.
The commonest malignant thyroid lesion was papillary carcinoma. Thyroid cancer was more common in females. Patients of papillary, medullary and follicular carcinomas were found in 3rd and 4th decades of life while poorly and undifferentiated carcinomas were diagnosed from 5th to 7th decades of life.
评估不同年龄和性别组甲状腺癌的发病率及类型。
这是一项在卡拉奇真纳研究生医学中心基础医学科学研究所病理科进行的回顾性研究。对2000年7月至2005年6月这5年间的998例甲状腺病变进行了回顾。研究苏木精和伊红染色切片以确定甲状腺恶性病变的类型和发病率。必要时进行特殊染色。
共回顾了998例甲状腺病变，其中153例为恶性。乳头状癌是最常见的恶性病变，发病率为90.2%，其次是髓样癌4.5%、滤泡癌2%、未分化癌2%，混合性髓样和乳头状癌以及低分化癌各占0.7%。女性占主导地位，为82.4%，男性为17.6%，男女比例为4.7:1。患者数量最多的年龄段为第4个十年，其次是第3个和第2个十年。
最常见的甲状腺恶性病变是乳头状癌。甲状腺癌在女性中更为常见。乳头状癌、髓样癌和滤泡癌患者多见于第3个和第4个十年，而低分化癌和未分化癌则在第5个至第7个十年被诊断出来。
