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患者对依巴斯汀速溶片在变应性鼻炎中起效时间和总体满意度的评估。

Patient assessment of onset of action and overall satisfaction with ebastine fast-dissolving tablets in allergic rhinitis.

机构信息

Hospital Universitari Germans Trias i Pujol, Carretera de Canyet, s/n 08916 Badalona, Spain.

出版信息

Expert Rev Pharmacoecon Outcomes Res. 2008 Aug;8(4):337-42. doi: 10.1586/14737167.8.4.337.

DOI:10.1586/14737167.8.4.337
PMID:20528340
Abstract

AIM

To evaluate patient perception of the onset of action and overall satisfaction with a fast-dissolving tablet (FDT) formulation of ebastine in patients with intermittent or persistent allergic rhinitis.

PATIENTS AND METHODS

This was a cross-sectional, multicenter, pharmacy-based survey involving adult patients (>18 years) with allergic rhinitis who presented with a prescription for ebastine FDT. Via a telephone interview, patients were asked to evaluate the characteristics of ebastine FDT in comparison with their previous experience with other antihistamines.

RESULTS

100 patients with allergic rhinitis were included in the study (41 had intermittent disease, 57 persistent disease and two with unknown disease states). Patients rated ebastine FDT very highly (mean scores: 4.5-4.7 out of a possible 5) for all characteristics related to convenience, such as easy to take, easy to carry around in a bag or pocket, suitable for taking anytime/anywhere, and convenient to use. A total of 85% of patients perceived ebastine FDTs onset of action to be fast or very fast, and 77% indicated that it acted faster than their usual antihistamine. A total of 96% were satisfied or very satisfied with ebastine FDT and 98% were interested in using the drug again.

CONCLUSIONS

Patients with rhinitis rate ebastine FDT very highly in terms of its formulation, convenience of use and its rapid onset of action. These characteristics resulted in a high level of individual satisfaction with the new formulation and a clear preference by the majority of patients to use ebastine FDT in the future.

摘要

目的

评估依巴斯汀速释片(FDT)治疗间歇性或持续性变应性鼻炎患者的起效时间和总体满意度。

患者和方法

这是一项横断面、多中心、基于药房的调查,涉及有过敏性鼻炎且开有依巴斯汀 FDT 处方的成年患者(>18 岁)。通过电话访谈,患者被要求评估依巴斯汀 FDT 的特征,并与他们之前使用其他抗组胺药的经验进行比较。

结果

100 例过敏性鼻炎患者纳入研究(41 例为间歇性疾病,57 例为持续性疾病,2 例疾病状态未知)。患者对依巴斯汀 FDT 的所有便利性特征给予了高度评价(评分均值:5 分制中 4.5-4.7 分),例如易于服用、便于携带于包或口袋中、适合随时随地服用以及使用方便。85%的患者认为依巴斯汀 FDT 的起效迅速或非常迅速,77%的患者表示它比他们常用的抗组胺药起效更快。96%的患者对依巴斯汀 FDT 感到满意或非常满意,98%的患者有兴趣再次使用该药物。

结论

鼻炎患者对依巴斯汀 FDT 的剂型、使用便利性和快速起效给予了高度评价。这些特征导致患者对新剂型的满意度非常高,大多数患者明确表示将来更愿意使用依巴斯汀 FDT。

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Clinical utility and patient adherence with ebastine for allergic rhinitis.
依巴斯汀治疗变应性鼻炎的临床效用及患者依从性
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