Specialist Registrar, Section of Surgery, Department of Surgery, Derby City Hospital, Uttoxeter Road, Derby DE22 3NE, UK.
Expert Rev Pharmacoecon Outcomes Res. 2006 Apr;6(2):195-206. doi: 10.1586/14737167.6.2.195.
For those involved in colorectal cancer management, the present day is an exciting time. There is a multitude of new techniques to be considered for early detection (screening). National population screening for 60-69-year olds in England is due to start this year. Also, minimally invasive surgical techniques and multimodal pathways of care are aiding faster recovery, and there are increasing options for both adjuvant and palliative therapies. This article summarizes how colorectal cancer is currently managed in the UK and discusses the developments that are in the early stages of clinical use or on the horizon. Current management is discussed in detail in the hope that innovators reading the article may identify areas for improvement and allow comparison of new interventions with what are currently the gold standards. As changes are moving so fast, this review will probably only relate to the next 10 years at most. It does not provide a detailed reference list to support all therapies but indicates the key publications that will enable more detailed reading.
对于参与结直肠癌管理的人来说，当今是一个令人兴奋的时代。有许多新的技术可以用于早期检测（筛查）。今年，英国将开始对 60-69 岁人群进行全国性筛查。此外，微创手术技术和多模式护理途径正在帮助患者更快地康复，并且辅助治疗和姑息治疗的选择也越来越多。本文总结了英国目前结直肠癌的治疗方法，并讨论了处于临床应用早期或即将出现的新进展。本文详细讨论了目前的治疗方法，希望阅读本文的创新者能够发现改进的领域，并将新的干预措施与当前的金标准进行比较。由于变化发展如此之快，本综述最多也只能涉及未来 10 年。它没有提供详细的参考列表来支持所有的治疗方法，但指出了关键的出版物，以便更详细地阅读。
