Lengheden A, Blomlöf L, Lindskog S
Department of Histology and Neurobiology, School of Dentistry, Karolinska Institutet, Stockholm, Sweden.
Scand J Dent Res. 1991 Apr;99(2):139-46. doi: 10.1111/j.1600-0722.1991.tb01876.x.
The effect of immediate permanent root-filling and immediate intracanal calcium hydroxide treatment on experimentally contaminated and necrotized periodontal membranes (PDM) in avulsed and subsequently replanted monkey teeth was studied. Almost the entire root surface in the non-endodontically treated control teeth were covered with inflammatory resorption. A significant shift towards ankylosis not associated with root resorption (greater than 80% of the total root surface area) was noted following calcium hydroxide treatment. About two thirds of the root surfaces from the teeth with permanent root fillings showed surface resorptions or ankylosis preceded by root resorption. The root surface area which would have been covered by inflammatory resorption, unless endodontic treatment had been implemented, were instead predominantly covered by either surface resorption (permanent root filling) or ankylosis (calcium hydroxide treatment). Ankylosis compared with surface resorption may in the long term lead to progressive loss of root substance due to replacement resorption. It was concluded that calcium hydroxide may be an excellent initial intracanal treatment in teeth with healthy PDM, but care should be taken not to risk unnecessary development of ankylosis by prolonged treatment of teeth with compromised PDM.
研究了即刻永久根管充填和即刻根管内氢氧化钙治疗对猴牙脱位再植后实验性污染和坏死牙周膜（PDM）的影响。未经牙髓治疗的对照牙几乎整个牙根表面都有炎性吸收。氢氧化钙治疗后，观察到向与牙根吸收无关的骨性粘连（大于牙根总面积的80%）显著转变。约三分之二进行了永久根管充填的牙齿的牙根表面出现了牙根吸收前的表面吸收或骨性粘连。如果未进行牙髓治疗，原本会被炎性吸收覆盖的牙根表面积，取而代之的是主要被表面吸收（永久根管充填）或骨性粘连（氢氧化钙治疗）所覆盖。与表面吸收相比，骨性粘连长期来看可能会因替代性吸收导致牙根物质逐渐丧失。得出的结论是，氢氧化钙可能是PDM健康的牙齿理想的初始根管内治疗药物，但对于PDM受损的牙齿，应注意避免因长期治疗而导致不必要的骨性粘连风险。
