Fadeyi Abayomi, Ogunmodede James A, Desalu Olufemi
Department of Medicine, University of Ilorin, Ilorin, Nigeria.
J Int Assoc Physicians AIDS Care (Chic). 2010 May-Jun;9(3):191-5. doi: 10.1177/1545109710368722.
Good adherence to highly active antiretroviral therapy (HAART) is required for viral suppression and prevention of drug resistance. Patients' adherence to HAART has not been determined since the commencement of HAART at the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria, over 5 years ago.
To determine the adherence level of people living with HIV/AIDS (PLWHA) to HAART and identify associated factors.
A semistructured questionnaire was administered to PLWHA, who were accessing treatment. Sociodemographic, lifestyle, HIV medical, and drug history were obtained from them. Adherence was self-reported. Good adherence was taking of 95% of the prescribed doses of HAART over the preceding 30 days before consultation.
Study participants were 253; majority, 58.5%, were females. About 70.8% of them had good adherence. Older age and male sex correlated better with adherence.
People living with HIV/AIDS were quite adherent to HAART. Male sex and older age were positive predictors of adherence. Adherence among the young age and females needs strengthening.
为实现病毒抑制和预防耐药性，需要良好地坚持高效抗逆转录病毒疗法（HAART）。自5年多前尼日利亚伊洛林大学伊洛林教学医院（UITH）开始实施HAART以来，患者对该疗法的坚持情况尚未得到确定。
确定艾滋病病毒/艾滋病患者（PLWHA）对HAART的坚持水平，并识别相关因素。
对正在接受治疗的PLWHA进行半结构化问卷调查。从他们那里获取社会人口统计学、生活方式、艾滋病医学和用药史信息。坚持情况由患者自我报告。良好的坚持是指在咨询前的前30天内服用了规定剂量95%的HAART。
研究参与者有253人；其中大多数（58.5%）为女性。约70.8%的参与者坚持情况良好。年龄较大和男性与坚持情况的相关性更好。
艾滋病病毒/艾滋病患者对HAART的坚持情况相当好。男性和年龄较大是坚持的积极预测因素。年轻患者和女性的坚持情况需要加强。
