加纳库马西大都市地区与艾滋病毒感染者药物依从性相关的社会人口学因素。

Socio-demographic factors associated with medication adherence among People Living with HIV in the Kumasi Metropolis, Ghana.

机构信息

Department of Health Promotion, Education and Disability Studies, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

College of Public Health, Medical and Veterinary Sciences, James Cook University, 4811, Townsville, QLD, Australia.

出版信息

AIDS Res Ther. 2022 Nov 14;19(1):50. doi: 10.1186/s12981-022-00474-z.

DOI:10.1186/s12981-022-00474-z

PMID:36376918

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9662109/

Abstract

BACKGROUND

Medication adherence is important to the survival of People Living with HIV (PLHIV) globally. Although, HIV viral load is reduced by antiretroviral therapy (ART), the number of people on ART continues to rise in Ghana. In the Kumasi Metropolis, Ghana, we looked at the socio-demographic factors associated with medication adherence among PLHIV.

METHODS

A quantitative study involving 420 PLHIV who sought healthcare at the Kumasi South Regional Hospital was conducted utilizing a cross-sectional study design. We employed a structured questionnaire to collect data on medication adherence using the eight-item Morisky Medication Adherence Scale (MMAS) and socio-demographic factors that influence medication adherence. The data were analysed using Stata 14.2. Frequencies and percentages were used to present the descriptive data. The association between socio-demographic factors and medication adherence among PLHIV was investigated using both univariate and multivariate analyses.

RESULTS

More than half (53.10%) of PLHIV adhered to ART. Place of residence was significantly established to be influencing medication adherence among PLHIV. PLHIV who were residing in urban centers (aOR = 3.61; CI = 2.24-5.82) were more likely to adhere to medication as compared to those who resided in rural areas.

CONCLUSION

Slightly more than half of PLHIV took their medicines as prescribed. Government and Policymakers such as the Ghana AIDS Commission, Ministry of Health, and Ghana Health Service should incorporate socio-demographic factors such as place of residence while creating and executing medication adherence initiatives to evaluate HIV management regimen for PLHIV.

摘要

背景

药物依从性对于全球艾滋病毒感染者（PLHIV）的生存至关重要。尽管抗逆转录病毒疗法（ART）可降低 HIV 病毒载量，但加纳接受 ART 的人数仍在继续增加。在加纳库马西都会区，我们研究了与 PLHIV 药物依从性相关的社会人口因素。

方法

采用横断面研究设计，对在库马西南部地区医院寻求医疗保健的 420 名 PLHIV 进行了一项定量研究。我们使用结构化问卷，采用 Morisky 药物依从性量表（MMAS）的 8 项评估药物依从性，并收集影响药物依从性的社会人口因素数据。使用 Stata 14.2 分析数据。使用频率和百分比呈现描述性数据。使用单变量和多变量分析调查 PLHIV 的社会人口因素与药物依从性之间的关联。