Vrettos Ioannis, Papageorgiou Sotiris, Economopoulou Christina, Pappa Vasiliki, Tsirigotis Panagiotis, Tountas Nikolaos, Economopoulos Theofanis, Dervenoulas John
Second Department of Internal Medicine, Propaedeutic, University of Athens, Medical School, Attikon University General Hospital, Haidari, Athens, Greece.
South Med J. 2010 Jul;103(7):676-8. doi: 10.1097/SMJ.0b013e3181e170f5.
Rosuvastatin, a statin indicated for patients with primary hypercholesterolemia, mixed dyslipidemia and familial hypercholesterolemia, is well tolerated by most patients. Its most common adverse effects are gastrointestinal derangement, muscle aches and hepatitis. One rare complication of statin treatment is severe thrombocytopenia. The case of a 65-year-old patient who developed severe thrombocytopenia while on rosuvastatin is presented, in addition to a review of the literature.
瑞舒伐他汀是一种适用于原发性高胆固醇血症、混合型血脂异常和家族性高胆固醇血症患者的他汀类药物，大多数患者对其耐受性良好。其最常见的不良反应是胃肠道紊乱、肌肉疼痛和肝炎。他汀类药物治疗的一种罕见并发症是严重血小板减少症。本文除了对文献进行综述外，还介绍了一名65岁患者在服用瑞舒伐他汀期间出现严重血小板减少症的病例。
