• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一名年轻女性的他汀类药物所致血小板减少症：病例报告及文献综述

Statin-Induced Thrombocytopenia in a Young Female: A Case Report and Literature Review.

作者信息

Shehryar Muhammad, Ashraf Muhammad Fawad, Uzair Ahmad Rana, Prasad Sakshi, Franca Hudson P

机构信息

Division of Research and Academic Affairs, Larkin Community Hospital Palm Springs Campus, Hialeah, USA.

Internal Medicine, Mayo Hospital, Lahore, PAK.

出版信息

Cureus. 2021 Nov 10;13(11):e19436. doi: 10.7759/cureus.19436. eCollection 2021 Nov.

DOI:10.7759/cureus.19436
PMID:34909340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8663800/
Abstract

The causal relationship of thrombocytopenia with statin intake has been described in many research articles. Our case discusses the refractory nature of thrombocytopenia in a 22-year-old female, one month following a daily intake of 20 mg atorvastatin. This is the first case ever of drug-induced refractory thrombocytopenia reported in a young patient. We will also discuss previously reported cases of drug-induced thrombocytopenia (DIT) in our manuscript.

摘要

许多研究文章都描述了血小板减少症与服用他汀类药物之间的因果关系。我们的病例讨论了一名22岁女性在每日服用20毫克阿托伐他汀一个月后出现的难治性血小板减少症。这是首次报道的年轻患者药物性难治性血小板减少症病例。我们还将在稿件中讨论先前报道的药物性血小板减少症（DIT）病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c49/8663800/6e2dd378a9f5/cureus-0013-00000019436-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c49/8663800/6e2dd378a9f5/cureus-0013-00000019436-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c49/8663800/6e2dd378a9f5/cureus-0013-00000019436-i01.jpg

相似文献

1
Statin-Induced Thrombocytopenia in a Young Female: A Case Report and Literature Review.一名年轻女性的他汀类药物所致血小板减少症：病例报告及文献综述
Cureus. 2021 Nov 10;13(11):e19436. doi: 10.7759/cureus.19436. eCollection 2021 Nov.
2
Atorvastatin-Induced Refractory Thrombocytopenia.阿托伐他汀诱导的难治性血小板减少症。
Cureus. 2021 Jan 5;13(1):e12502. doi: 10.7759/cureus.12502.
3
Simvastatin and amlodipine induced thrombocytopenia in the same patient: double trouble and a literature review.辛伐他汀和氨氯地平致同一患者血小板减少症：双重麻烦并文献复习。
J Clin Pharm Ther. 2013 Jun;38(3):246-8. doi: 10.1111/jcpt.12051. Epub 2013 Feb 26.
4
Drug-induced thrombocytopenia: a systematic review of published case reports.药物性血小板减少症：已发表病例报告的系统评价
Ann Intern Med. 1998 Dec 1;129(11):886-90. doi: 10.7326/0003-4819-129-11_part_1-199812010-00009.
5
Antimicrobial drug-induced thrombocytopenia: a review of the literature.抗菌药物诱导的血小板减少症：文献综述。
Semin Thromb Hemost. 2012 Nov;38(8):818-29. doi: 10.1055/s-0032-1328882. Epub 2012 Oct 18.
6
Platelet measurements versus discharge diagnoses for identification of patients with potential drug-induced thrombocytopenia: a cross-sectional study in the Netherlands.血小板测量值与出院诊断用于识别潜在药物性血小板减少症患者：荷兰的一项横断面研究
Drug Saf. 2009;32(1):69-76. doi: 10.2165/00002018-200932010-00006.
7
Drug and medical cost effects of a drug formulary change with therapeutic interchange for statin drugs in a multistate managed Medicaid organization.在一个多州管理的医疗补助组织中，药物处方集变更及他汀类药物治疗性互换的药物和医疗成本影响。
J Manag Care Pharm. 2006 May;12(4):331-40. doi: 10.18553/jmcp.2006.12.4.331.
8
Atorvastatin and Aspirin as Adjuvant Therapy in Patients with SARS-CoV-2 Infection: A structured summary of a study protocol for a randomised controlled trial.阿托伐他汀和阿司匹林作为 SARS-CoV-2 感染患者的辅助治疗：一项随机对照试验的研究方案的结构化总结。
Trials. 2020 Oct 30;21(1):902. doi: 10.1186/s13063-020-04840-y.
9
Drug-induced immune thrombocytopenia.药物性免疫性血小板减少症
Drug Saf. 2004;27(15):1243-52. doi: 10.2165/00002018-200427150-00007.
10
Severe immune thrombocytopenia following diphtheria, tetanus, pertussis and polio vaccination in a 36-year-old Caucasian woman: a case report.一名 36 岁白人女性接种白喉、破伤风、百日咳和脊灰疫苗后出现严重免疫性血小板减少症：病例报告。
Eur J Med Res. 2022 May 3;27(1):63. doi: 10.1186/s40001-022-00686-z.

本文引用的文献

1
Atorvastatin-Induced Refractory Thrombocytopenia.阿托伐他汀诱导的难治性血小板减少症。
Cureus. 2021 Jan 5;13(1):e12502. doi: 10.7759/cureus.12502.
2
Statins in Stroke.他汀类药物在脑卒中中的应用。
Curr Med Chem. 2019;26(33):6174-6185. doi: 10.2174/0929867326666190620104539.
3
[Thrombocytopenia purpura, myositis and cytolitic hepatitis: a rare association linked with atorvastatin].
Mali Med. 2013;28(1):49-51.
4
Improving the assessment of adverse drug reactions using the Naranjo Algorithm in daily practice: The Japan Adverse Drug Events Study.利用 Naranjo 算法在日常实践中改进药物不良反应评估：日本药物不良事件研究。
Pharmacol Res Perspect. 2018 Feb;6(1). doi: 10.1002/prp2.373.
5
Primary and Secondary Prevention of Acute Coronary Syndromes: The Role of the Statins.急性冠状动脉综合征的一级和二级预防：他汀类药物的作用
Recent Adv Cardiovasc Drug Discov. 2014;9(2):97-105. doi: 10.2174/1574890110666150708112349.
6
Simvastatin and amlodipine induced thrombocytopenia in the same patient: double trouble and a literature review.辛伐他汀和氨氯地平致同一患者血小板减少症：双重麻烦并文献复习。
J Clin Pharm Ther. 2013 Jun;38(3):246-8. doi: 10.1111/jcpt.12051. Epub 2013 Feb 26.
7
Atorvastatin-related thrombocytopenic purpura.阿托伐他汀相关的血小板减少性紫癜。
BMJ Case Rep. 2010 May 19;2010:bcr01.2010.2614. doi: 10.1136/bcr.01.2010.2614.
8
Rosuvastatin-induced thrombocytopenia.瑞舒伐他汀诱导的血小板减少症。
South Med J. 2010 Jul;103(7):676-8. doi: 10.1097/SMJ.0b013e3181e170f5.
9
Drug-induced immune thrombocytopenia: pathogenesis, diagnosis, and management.药物性免疫性血小板减少症：发病机制、诊断与管理
J Thromb Haemost. 2009 Jun;7(6):911-8. doi: 10.1111/j.1538-7836.2009.03360.x. Epub 2009 Apr 2.
10
Drug-induced thrombocytopenia.药物性血小板减少症
Arch Pathol Lab Med. 2009 Feb;133(2):309-14. doi: 10.5858/133.2.309.