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玻璃体内注射贝伐单抗后即将发生的视网膜中央静脉阻塞进展为缺血性变体。

Progression of impending central retinal vein occlusion to the ischemic variant following intravitreal bevacizumab.

作者信息

Kim Na Rae, Chin Hee Seung

机构信息

Department of Ophthalmology, Inha University School of Medicine, #7-206, Shinheung-dong, Jung-gu, Incheon, Korea.

出版信息

Korean J Ophthalmol. 2010 Jun;24(3):179-81. doi: 10.3341/kjo.2010.24.3.179. Epub 2010 Jun 5.

Abstract

A 60-year-old woman who had experienced two episodes of amaurosis fugax in her right eye presented with vision loss. Two weeks earlier, at a private clinic, she was diagnosed with impending central retinal vein occlusion (CRVO) of the right eye and received an intravitreal injection of bevacizumab. Two weeks after this injection she was diagnosed with ischemic CRVO. At 11-weeks post-presentation, extremely ischemic features were observed with fluorescein angiographic findings of severe vascular attenuation and extensive retinal capillary obliteration. At 22-weeks post-presentation she was diagnosed with neovascular glaucoma; she experienced no visual improvement over the following several months.

摘要

一名60岁女性右眼曾经历过两次一过性黑矇发作,此次出现视力丧失。两周前,在一家私人诊所,她被诊断为右眼即将发生视网膜中央静脉阻塞(CRVO),并接受了玻璃体腔内注射贝伐单抗。此次注射两周后,她被诊断为缺血性CRVO。就诊后11周时,荧光素血管造影显示出极缺血的特征,表现为严重的血管变细和广泛的视网膜毛细血管闭塞。就诊后22周时,她被诊断为新生血管性青光眼;在接下来的几个月里,她的视力没有改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7d/2882084/91e48044f446/kjo-24-179-g001.jpg

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