Department of Ophthalmology, Osaka Medical College, Takatsuki, Japan.
Biomed Res Int. 2017;2017:4816527. doi: 10.1155/2017/4816527. Epub 2017 Aug 20.
Retinal vein occlusion (RVO) is a common vascular disease of retina; however, the pathomechanism leading to RVO is not yet clear. In general, increasing age, hypertension, arteriosclerosis, diabetes mellitus, dyslipidemia, cardiovascular disorder, and cerebral stroke are systemic risk factors of RVO. However, RVO often occur in the unilateral eye and sometimes develop in young subjects who have no arteriosclerosis. In addition, RVO show different variations on the degrees of severity; some RVO are resolved without any treatment and others develop vision-threatening complications such as macular edema, combined retinal artery occlusion, vitreous hemorrhage, and glaucoma. Clinical conditions leading to RVO are still open to question. In this review, we discuss how to treat RVO in practice by presenting some RVO cases. We also deliver possible pathomechanisms of RVO through our clinical experience and animal experiments.
视网膜静脉阻塞（RVO）是一种常见的视网膜血管疾病；然而，导致 RVO 的发病机制尚不清楚。一般来说，年龄增长、高血压、动脉硬化、糖尿病、血脂异常、心血管疾病和脑卒中等是 RVO 的全身性危险因素。然而，RVO 常发生于单侧眼，有时也发生于无动脉硬化的年轻患者。此外，RVO 在严重程度上表现出不同的变化；一些 RVO 未经任何治疗即可自行消退，而另一些则会出现威胁视力的并发症，如黄斑水肿、合并视网膜动脉阻塞、玻璃体积血和青光眼。导致 RVO 的临床情况仍存在疑问。在这篇综述中，我们通过介绍一些 RVO 病例，讨论了如何在实践中治疗 RVO。我们还通过临床经验和动物实验，阐述了 RVO 的可能发病机制。
