Shanwell A, Ringdén O, Wiechel B, Rumin S, Akerblom O
Stockholm Blood Transfusion Service, Huddinge, Sweden.
Vox Sang. 1991;60(1):23-7. doi: 10.1111/j.1423-0410.1991.tb00866.x.
Bone marrow transplant recipients at Huddinge Hospital have routinely received single-donor platelet concentrates (PC) from blood group O donors. These PC contain approximately 350 ml plasma, which is incompatible with patients of group A, B and AB. In 27 patients transplanted with an ABO-identical bone marrow, serological investigations have been performed every week after transplantation (median 6 weeks, range 3-14). Nine of 11 recipients with blood group A developed a positive direct antiglobulin test (DAT) after PC transfusions, while none of 15 patients of blood group O developed a positive DAT. Anti-A could be eluted in DAT-positive cases. In no case was there any clinical sign of hemolysis. Nor did recipients of groups A, B or AB (n = 34) require more red blood cells or PC transfusions compared to recipients of group O (n = 47).
胡丁厄医院的骨髓移植受者常规接受来自O型血供者的单供者血小板浓缩物（PC）。这些PC含有约350毫升血浆，这与A、B和AB血型的患者不相容。在27例接受ABO血型相同骨髓移植的患者中，移植后每周进行血清学检查（中位数为6周，范围为3 - 14周）。11例A型血受者中有9例在输注PC后直接抗球蛋白试验（DAT）呈阳性，而15例O型血患者中无一例DAT呈阳性。在DAT阳性病例中可洗脱出血清抗A。无一例出现溶血的临床症状。与O型血受者（n = 47）相比，A、B或AB型血受者（n = 34）也不需要更多的红细胞或PC输注。
