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引用本文的文献

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The antileishmanial activity of isoforms 6- and 8-selective histone deacetylase inhibitors.6型和8型选择性组蛋白去乙酰化酶抑制剂的抗利什曼原虫活性
Bioorg Med Chem Lett. 2014 Oct 15;24(20):4826-30. doi: 10.1016/j.bmcl.2014.08.060. Epub 2014 Sep 4.
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Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei.具有针对非洲锥虫 Trypanosoma brucei 高活性的人组蛋白去乙酰化酶抑制剂。
Bioorg Med Chem Lett. 2012 Mar 1;22(5):1886-90. doi: 10.1016/j.bmcl.2012.01.072. Epub 2012 Jan 28.
3
Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton.来源于三环酮内酯骨架的非肽类大环组蛋白去乙酰化酶抑制剂。
J Med Chem. 2010 Aug 26;53(16):6100-11. doi: 10.1021/jm100507q.

本文引用的文献

1
Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group.含三唑连接帽基团的组蛋白去乙酰化酶抑制剂的抗疟和抗利什曼原虫活性。
Bioorg Med Chem. 2010 Jan 1;18(1):415-25. doi: 10.1016/j.bmc.2009.10.042. Epub 2009 Oct 27.
2
Targeting histone deacetylase inhibitors for anti-malarial therapy.靶向组蛋白去乙酰化酶抑制剂用于抗疟治疗。
Curr Top Med Chem. 2009;9(3):292-308. doi: 10.2174/156802609788085313.
3
Inhibition of Plasmodium falciparum proliferation in vitro by double-stranded RNA directed against malaria histone deacetylase.靶向疟疾组蛋白去乙酰化酶的双链RNA对恶性疟原虫体外增殖的抑制作用
Biochem Biophys Res Commun. 2009 Apr 3;381(2):144-7. doi: 10.1016/j.bbrc.2009.01.165. Epub 2009 Jan 31.
4
Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum.恶性疟原虫I类组蛋白去乙酰化酶小分子抑制剂的鉴定与表征
J Med Chem. 2009 Apr 23;52(8):2185-7. doi: 10.1021/jm801654y.
5
Non-peptide macrocyclic histone deacetylase inhibitors.非肽大环组蛋白脱乙酰酶抑制剂
J Med Chem. 2009 Jan 22;52(2):456-68. doi: 10.1021/jm801128g.
6
Antimalarial activity of phenylthiazolyl-bearing hydroxamate-based histone deacetylase inhibitors.含苯并噻唑基的异羟肟酸类组蛋白去乙酰化酶抑制剂的抗疟活性
Antimicrob Agents Chemother. 2008 Oct;52(10):3467-77. doi: 10.1128/AAC.00439-08. Epub 2008 Jul 21.
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Antileishmanial activity of azithromycin against Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, and Leishmania (Leishmania) chagasi.阿奇霉素对亚马逊利什曼原虫（利什曼原虫属）、巴西利什曼原虫（维扬尼利什曼原虫属）和恰加斯利什曼原虫（利什曼原虫属）的抗利什曼原虫活性。
Am J Trop Med Hyg. 2008 May;78(5):745-9.
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Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy.恶性疟原虫组蛋白去乙酰化酶1（PfHDAC-1）的结构见解：抗疟治疗开发的新靶点。
Bioorg Med Chem. 2008 May 1;16(9):5254-65. doi: 10.1016/j.bmc.2008.03.005. Epub 2008 Mar 6.
9
Potent antimalarial activity of histone deacetylase inhibitor analogues.组蛋白去乙酰化酶抑制剂类似物的强效抗疟活性。
Antimicrob Agents Chemother. 2008 Apr;52(4):1454-61. doi: 10.1128/AAC.00757-07. Epub 2008 Jan 22.
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The amastigote forms of Leishmania are experts at exploiting host cell processes to establish infection and persist.利什曼原虫的无鞭毛体形式善于利用宿主细胞过程来建立感染并持续存在。
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A structure-activity relationship study of the antimalarial and antileishmanial activities of nonpeptide macrocyclic histone deacetylase inhibitors.

作者信息

Guerrant William, Mwakwari Sandra C, Chen Po C, Khan Shabana I, Tekwani Babu L, Oyelere Adegboyega K

机构信息

Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332-0400, USA.

出版信息

ChemMedChem. 2010 Aug 2;5(8):1232-5. doi: 10.1002/cmdc.201000087.

DOI:10.1002/cmdc.201000087
PMID:20533500
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3138184/
Abstract
摘要