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Catastrophic squamous cell carcinoma in lung transplant patients treated with voriconazole.

作者信息

Ibrahim Sherrif F, Singer Jonathan P, Arron Sarah T

机构信息

Department of Dermatology, University of California at San Francisco, San Francisco, California, USA.

出版信息

Dermatol Surg. 2010 Nov;36(11):1752-5. doi: 10.1111/j.1524-4725.2010.01596.x.

DOI:10.1111/j.1524-4725.2010.01596.x
PMID:20533939
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3046628/
Abstract
摘要

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Catastrophic squamous cell carcinoma in lung transplant patients treated with voriconazole.接受伏立康唑治疗的肺移植患者发生的灾难性鳞状细胞癌。
Dermatol Surg. 2010 Nov;36(11):1752-5. doi: 10.1111/j.1524-4725.2010.01596.x.
2
Voriconazole exposure and geographic location are independent risk factors for squamous cell carcinoma of the skin among lung transplant recipients.伏立康唑暴露和地理位置是肺移植受者皮肤鳞状细胞癌的独立危险因素。
J Heart Lung Transplant. 2010 Nov;29(11):1240-4. doi: 10.1016/j.healun.2010.05.022. Epub 2010 Jun 29.
3
Increased incidence of cutaneous squamous cell carcinoma in lung transplant recipients taking long-term voriconazole.长期服用伏立康唑的肺移植受者皮肤鳞状细胞癌发病率增加。
J Heart Lung Transplant. 2012 Nov;31(11):1177-81. doi: 10.1016/j.healun.2012.05.003. Epub 2012 Jul 27.
4
Duration of voriconazole exposure: an independent risk factor for skin cancer after lung transplantation.伏立康唑暴露时间：肺移植后皮肤癌的独立危险因素。
Dermatol Surg. 2012 Aug;38(8):1369-74. doi: 10.1111/j.1524-4725.2012.02418.x. Epub 2012 May 2.
5
Severe photosensitivity causing multifocal squamous cell carcinomas secondary to prolonged voriconazole therapy.长期伏立康唑治疗导致严重光敏反应，继发多灶性鳞状细胞癌。
Clin Infect Dis. 2007 Mar 1;44(5):e55-6. doi: 10.1086/511685. Epub 2007 Jan 23.
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Aggressive cutaneous squamous cell carcinoma associated with prolonged voriconazole therapy in a renal transplant patient.肾移植患者长期使用伏立康唑治疗相关的侵袭性皮肤鳞状细胞癌
Am J Transplant. 2008 Apr;8(4):877-80. doi: 10.1111/j.1600-6143.2007.02140.x. Epub 2008 Feb 5.
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High cumulative dose exposure to voriconazole is associated with cutaneous squamous cell carcinoma in lung transplant recipients.高累积剂量的伏立康唑暴露与肺移植受者的皮肤鳞状细胞癌有关。
J Heart Lung Transplant. 2012 Jul;31(7):694-9. doi: 10.1016/j.healun.2012.02.033. Epub 2012 Apr 6.
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Phototoxicity and photocarcinogenesis associated with voriconazole.与伏立康唑相关的光毒性和光致癌作用。
Med Mal Infect. 2011 Dec;41(12):639-45. doi: 10.1016/j.medmal.2011.09.016. Epub 2011 Nov 3.
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Chronic phototoxicity and aggressive squamous cell carcinoma of the skin in children and adults during treatment with voriconazole.儿童和成人在使用伏立康唑治疗期间出现慢性光毒性和侵袭性鳞状细胞癌。
J Am Acad Dermatol. 2010 Jan;62(1):31-37. doi: 10.1016/j.jaad.2009.09.033. Epub 2009 Nov 6.
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Voriconazole and squamous cell carcinoma after lung transplantation: A multicenter study.肺移植后伏立康唑和鳞状细胞癌：一项多中心研究。
Am J Transplant. 2018 Jan;18(1):113-124. doi: 10.1111/ajt.14500. Epub 2017 Oct 16.

引用本文的文献

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Voriconazole enhances UV-induced DNA damage by inhibiting catalase and promoting oxidative stress.伏立康唑通过抑制过氧化氢酶和促进氧化应激增强 UV 诱导的 DNA 损伤。
Exp Dermatol. 2020 Jan;29(1):29-38. doi: 10.1111/exd.14038. Epub 2019 Oct 29.
2
Adverse Effects Associated with Long-Term Administration of Azole Antifungal Agents.长期应用唑类抗真菌药物相关的不良反应。
Drugs. 2019 Jun;79(8):833-853. doi: 10.1007/s40265-019-01127-8.
3
Recurrent and metastatic squamous cell carcinoma in lung transplant recipient on voriconazole: Lessons learned.肺移植受者接受伏立康唑治疗时发生复发性和转移性鳞状细胞癌：经验教训。
JAAD Case Rep. 2015 Nov 24;1(6):S12-5. doi: 10.1016/j.jdcr.2015.09.015. eCollection 2015 Nov.
4
Voriconazole N-oxide and its ultraviolet B photoproduct sensitize keratinocytes to ultraviolet A.伏立康唑N-氧化物及其紫外线B光产物使角质形成细胞对紫外线A敏感。
Br J Dermatol. 2015 Sep;173(3):751-9. doi: 10.1111/bjd.13862. Epub 2015 Jul 20.
5
High cumulative dose exposure to voriconazole is associated with cutaneous squamous cell carcinoma in lung transplant recipients.高累积剂量的伏立康唑暴露与肺移植受者的皮肤鳞状细胞癌有关。
J Heart Lung Transplant. 2012 Jul;31(7):694-9. doi: 10.1016/j.healun.2012.02.033. Epub 2012 Apr 6.
6
Long-term voriconazole and skin cancer: is there cause for concern?长期伏立康唑治疗与皮肤癌：是否需要担忧？
Curr Infect Dis Rep. 2011 Dec;13(6):536-43. doi: 10.1007/s11908-011-0220-x.
7
Skin cancer in transplant recipients, out of the woods. Scientific retreat of the ITSCC and SCOPE.移植受者中的皮肤癌，脱离险境。ITSCC 和 SCOPE 的科学务虚会。
Am J Transplant. 2011 Aug;11(8):1584-91. doi: 10.1111/j.1600-6143.2011.03645.x.

本文引用的文献

1
Multiple aggressive squamous cell carcinomas associated with prolonged voriconazole therapy in four immunocompromised patients.四例免疫功能低下患者长期伏立康唑治疗相关的侵袭性鳞状细胞癌。
Clin Microbiol Infect. 2010 Sep;16(9):1362-4. doi: 10.1111/j.1469-0691.2009.03124.x.
2
Chronic phototoxicity and aggressive squamous cell carcinoma of the skin in children and adults during treatment with voriconazole.儿童和成人在使用伏立康唑治疗期间出现慢性光毒性和侵袭性鳞状细胞癌。
J Am Acad Dermatol. 2010 Jan;62(1):31-37. doi: 10.1016/j.jaad.2009.09.033. Epub 2009 Nov 6.
3
Multifocal squamous cell carcinomas in an HIV-infected patient with a long-term voriconazole therapy.一名长期接受伏立康唑治疗的HIV感染患者发生多灶性鳞状细胞癌。
AIDS. 2008 Apr 23;22(7):905-6. doi: 10.1097/QAD.0b013e3282f706a9.
4
Aggressive cutaneous squamous cell carcinoma associated with prolonged voriconazole therapy in a renal transplant patient.肾移植患者长期使用伏立康唑治疗相关的侵袭性皮肤鳞状细胞癌
Am J Transplant. 2008 Apr;8(4):877-80. doi: 10.1111/j.1600-6143.2007.02140.x. Epub 2008 Feb 5.
5
Fatal diffuse alveolar damage in two lung transplant patients treated with cetuximab.两名接受西妥昔单抗治疗的肺移植患者发生致命性弥漫性肺泡损伤。
J Heart Lung Transplant. 2007 Dec;26(12):1340-4. doi: 10.1016/j.healun.2007.09.019.
6
Severe photosensitivity causing multifocal squamous cell carcinomas secondary to prolonged voriconazole therapy.长期伏立康唑治疗导致严重光敏反应，继发多灶性鳞状细胞癌。
Clin Infect Dis. 2007 Mar 1;44(5):e55-6. doi: 10.1086/511685. Epub 2007 Jan 23.
7
Skin cancers in organ transplant recipients.器官移植受者中的皮肤癌
J Am Acad Dermatol. 2006 Jun;54(6):1115. doi: 10.1016/j.jaad.2006.02.042.
8
Incidence of skin cancer in 5356 patients following organ transplantation.5356例器官移植患者皮肤癌的发病率。
Br J Dermatol. 2000 Sep;143(3):513-9.
9
Skin cancer in kidney and heart transplant recipients and different long-term immunosuppressive therapy regimens.肾移植和心脏移植受者的皮肤癌及不同的长期免疫抑制治疗方案。
J Am Acad Dermatol. 1999 Feb;40(2 Pt 1):177-86. doi: 10.1016/s0190-9622(99)70185-4.