Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institute of Health, Bethesda, MD, USA.
J Am Geriatr Soc. 2010 Jul;58(7):1333-40. doi: 10.1111/j.1532-5415.2010.02904.x. Epub 2010 Jun 1.
To determine the distribution of influenza vaccine coverage in the United States in 2008.
Cross-sectional analysis.
The 2008 Behavioral Risk Factor Surveillance Survey, which employs random-digit dialing to interview noninstitutionalized adults in the United States and territories.
Two hundred forty-nine thousand seven hundred twenty-three persons aged 50 and older.
Participants were asked whether they had had an influenza vaccination during the previous 12 months.
In 2008, 42.0% of adults aged 50 to 64 and 69.5% of adults aged 65 and older reported receiving an influenza vaccination in the past 12 months. Vaccine coverage generally increased with advancing age (P<.001), higher levels of education (P<.001) and total household income (P<.001), and greater morbidity (P<.001). In participants aged 50 to 64, vaccine prevalence was lower in men (39.9%) than in women (44.1%; P<.001), although no significant differences were observed in older adults. Within each 5-year interval of age, non-Hispanic blacks and Hispanics had significantly lower vaccine prevalence than non-Hispanic whites (P<.001 for all comparisons). For participants aged 65 and older, non-Hispanic blacks and Hispanics were 56% (adjusted prevalence ratio (PR)=1.56, 95% confidence interval (CI)=1.48, 1.64) and 44% (adjusted PR=1.44, 95% CI=1.35, 1.54) more likely, respectively, to be unvaccinated than non-Hispanic whites, adjusting for age and sex. Racial and ethnic disparities in vaccine coverage narrowed with increasing number of diseases, although these disparities remained significant in older adults with two or more diseases (P<.05).
There were large disparities in influenza vaccine coverage in 2008, particularly across race and ethnicity and socioeconomic position. Accordingly, more targeted interventions are needed to improve vaccine delivery to disadvantaged segments of the U.S. population.
确定 2008 年美国流感疫苗接种率的分布情况。
横断面分析。
2008 年行为风险因素监测调查,该调查采用随机数字拨号的方式对美国和属地的非机构化成年人进行访谈。
24.9723 名年龄在 50 岁及以上的人。
询问参与者在过去 12 个月中是否接种过流感疫苗。
2008 年,50 至 64 岁的成年人中有 42.0%,65 岁及以上的成年人中有 69.5%报告在过去 12 个月中接种了流感疫苗。疫苗接种率通常随年龄的增长而增加(P<.001),受教育程度较高(P<.001)和家庭总收入较高(P<.001)以及更高的发病率(P<.001)。在 50 至 64 岁的参与者中,男性(39.9%)的疫苗接种率低于女性(44.1%;P<.001),但在老年人中未观察到显著差异。在每个 5 岁年龄间隔内,非西班牙裔黑人和西班牙裔的疫苗接种率明显低于非西班牙裔白人(所有比较均 P<.001)。对于 65 岁及以上的参与者,非西班牙裔黑人和西班牙裔人未接种疫苗的可能性分别是非西班牙裔白人的 56%(调整后的患病率比(PR)=1.56,95%置信区间(CI)=1.48,1.64)和 44%(调整后的 PR=1.44,95%CI=1.35,1.54),调整年龄和性别后差异有统计学意义。疫苗接种率的种族和民族差异随着疾病数量的增加而缩小,但在有两种或更多疾病的老年人中,这些差异仍然显著(P<.05)。
2008 年流感疫苗接种率存在很大差异,特别是在种族和民族以及社会经济地位方面。因此,需要采取更有针对性的干预措施,以改善美国弱势人群的疫苗接种。