Department of Dermatology, Farhat Hached Hospital, Sousse, Tunisia.
Int J Dermatol. 2010 May;49(5):513-6. doi: 10.1111/j.1365-4632.2010.04296.x.
To determine the pattern of infectious agents causing tinea capitis (TC) in adult patients in the center of Tunisia.
From January 1990 to December 2005, we have retrospectively collected all cases of adult TC, confirmed by the mycological examination.
Sixty patients (18 male, 42 female) with a mean age of 34.5 years were diagnosed as having adult TC among a total number of 1137 cases of TC (5.27%). Clinical features were polymorphic and diagnosis was made on mycological examination. Culture identified Trichophyton violaceum in 36 cases (60%), Microsporum canis in 12 cases (20%), Trichophyton schoenleini in 7 cases (12%), Trichophyton verrucosum in two cases (3.5%), and Trichophyton mentagrophytes and Trichophyton rubrum in one case (each 1.77%). Culture was negative in one case (1.77%). Treatment consisted of administration of Griseofulvin(20–25 mg/kg/d) during 6–8 weeks associated with antifungal topics. A complete recovery was noted in 55 cases (92%) and a relapse occurred in two patients (3.5%). A scary alopecia was observed in one patient (1.77%) and two patients were lost to follow-up.
Trichophyton violaceum remains the most common etiological agent of adult TC in Tunisia. Microsporum canis is rising rapidly most notably due to the high frequency of asymptomatic carriage by domestic animals [corrected].
确定突尼斯中心成人头癣（TC）感染病原体的模式。
从 1990 年 1 月至 2005 年 12 月，我们回顾性地收集了所有经真菌学检查证实的成人 TC 病例。
在总共 1137 例 TC（5.27%）病例中，诊断出 60 例（18 名男性，42 名女性）成年 TC 患者，平均年龄为 34.5 岁。临床特征呈多态性，诊断依据为真菌学检查。培养鉴定出 36 例（60%）紫色毛癣菌、12 例（20%）犬小孢子菌、7 例（12%）小孢子菌、2 例（3.5%）疣状毛癣菌和 1 例（1.77%）须癣毛癣菌和红色毛癣菌。1 例（1.77%）培养结果为阴性。治疗包括给予灰黄霉素（20-25mg/kg/d），持续 6-8 周，同时使用抗真菌药物。55 例（92%）患者完全康复，2 例（3.5%）患者复发。1 例（1.77%）患者出现可怕的脱发，2 例（3.5%）患者失访。
紫色毛癣菌仍然是突尼斯成人 TC 最常见的病因。犬小孢子菌的发病率迅速上升，主要是由于其在宠物身上无症状携带的频率很高。
