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功能性鼻内镜鼻窦手术治疗真菌球型鼻窦炎的患者满意度及治疗效果

Patient satisfaction and treatment outcome of fungus ball rhinosinusitis treated by functional endoscopic sinus surgery.

作者信息

Lai Jui-Chung, Lee Hong-Shen, Chen Mu-Kuan, Tsai Yao-Lung

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, 135 Nanhsiao St, Changhua, Taiwan.

出版信息

Eur Arch Otorhinolaryngol. 2011 Feb;268(2):227-30. doi: 10.1007/s00405-010-1299-7. Epub 2010 Jun 10.

Abstract

Fungal rhinosinusitis is an important clinical problem with diverse manifestations. Although many literatures had found low recurrence rate after surgical treatment of fungus ball rhinosinusitis, patient satisfaction and treatment outcomes (symptom-free and symptom improvement rate, etc.) for fungus ball sinusitis are not yet well established. The purpose of this study is to estimate the patient satisfaction and treatment outcome in patients with fungus ball rhinosinusitis undergoing functional endoscopic sinus surgery (FESS). Medical records of consecutive patients with diagnosed fungus ball rhinosinusitis treated by FESS between 1995 and 2005 were reviewed retrospectively. The post-operative improvement in individual symptom was assessed by chart review and telephone visiting. Ninety consecutive patients (21 men and 69 women) were eligible for the study. Six patients (7%) presented bilateral fungus ball rhinosinusitis. Multiple paranasal sinus fungus ball involvements were found in 48 patients (53%). Complete resolution of complaints with respect to nasal discharge, postnasal drip, cough with sputum, nasal bleeding, fetid odor of nose, olfactory dysfunction, nasal obstruction, headache, and facial pain or pressure were described in 74 patients (82%). The overall patient satisfaction rate was 96%. The estimated recurrence rate of fungus ball rhinosinusitis treated with FESS was 3%, with a mean follow-up of 81 months. Treatment protocol of fungus ball rhinosinusitis with FESS and without postoperative antifungal drugs is efficient because of very low recurrence rate, high patient satisfaction, and very high symptom-free rate. Furthermore, the obvious difference of symptom-free rate between fungus ball rhinosinusitis and chronic rhinosinusitis highlights the need of further studies to discover the pathophysiology of fungal sinusitis.

摘要

真菌性鼻窦炎是一个具有多种表现的重要临床问题。尽管许多文献发现真菌球型鼻窦炎手术治疗后的复发率较低,但真菌球型鼻窦炎的患者满意度和治疗效果(无症状和症状改善率等)尚未得到充分确立。本研究的目的是评估接受功能性鼻内镜鼻窦手术(FESS)的真菌球型鼻窦炎患者的满意度和治疗效果。回顾性分析了1995年至2005年间连续接受FESS治疗的确诊真菌球型鼻窦炎患者的病历。通过病历审查和电话随访评估个体症状的术后改善情况。连续90例患者(21例男性和69例女性)符合研究条件。6例患者(7%)表现为双侧真菌球型鼻窦炎。48例患者(53%)发现多个鼻窦真菌球受累。74例患者(82%)描述了鼻分泌物、鼻后滴漏、咳痰咳嗽、鼻出血、鼻臭、嗅觉障碍、鼻塞、头痛以及面部疼痛或压迫感等症状完全缓解。总体患者满意度为96%。接受FESS治疗的真菌球型鼻窦炎的估计复发率为3%,平均随访81个月。由于复发率极低、患者满意度高且无症状率极高,FESS治疗真菌球型鼻窦炎且术后不使用抗真菌药物的治疗方案是有效的。此外,真菌球型鼻窦炎和慢性鼻窦炎之间无症状率的明显差异凸显了进一步研究以发现真菌性鼻窦炎病理生理学的必要性。

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