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秘鲁亚马逊地区青少年期早、晚期和成年母亲所生新生儿低体重的比较。

A comparison of low birth weight among newborns of early adolescents, late adolescents, and adult mothers in the Peruvian Amazon.

机构信息

Department of Epidemiology, Biostatistics, & Occupational Health, McGill University, Montreal, QC, Canada.

出版信息

Matern Child Health J. 2011 Jul;15(5):587-96. doi: 10.1007/s10995-010-0621-8.

Abstract

To compare low birth weight (LBW: <2,500 g) between infants born to adolescent and adult mothers in Iquitos, Peru. A random sample of 4,467 records of women who delivered at the Hospital Apoyo Iquitos between 2005 and 2007 was collected from hospital birth registries. Multivariate logistic and linear regression analyses were performed to compare LBW in newborns of adolescents (10-14, 15-19 years) and adults (≥20 years) and then for primiparous mothers with a normal gestational age, adjusting for newborn sex, antenatal care, and location of the mother's residence. A total of 4,384 mothers had had a singleton live birth and 1,501 were primiparous with a normal gestational age. Early and late adolescents had significantly greater odds of having a LBW infant than adults (OR = 2.28, 95%CI: 1.09, 4.78; OR = 1.67, 95%CI: 1.30, 2.14, respectively). For primiparous mothers with a normal gestational age, the same was true only for early adolescents (OR = 3.07, 95%CI: 1.09, 8.61). There were significant differences in mean birth weight between adults (3178.7 g) and both adolescent age groups overall (10-14 years: 2848.9 g; 15-19 years: 2998.3 g) and for primiparous mothers with a normal gestational age (10-14 years: 2900.8 g; 15-19 years: 3059.2 g; ≥20 years: 3151.8 g). Results suggest there is an important difference between adolescent and adult mothers in terms of newborn birth weight, especially among early adolescents. Future research on LBW and possibly other adverse birth outcomes should consider early adolescents as a separate sub-group of higher risk.

摘要

比较秘鲁伊基托斯市青春期和成年母亲所生婴儿的低出生体重(LBW:<2500 克)。从医院出生登记处收集了 2005 年至 2007 年期间在阿波约伊基托斯医院分娩的 4467 名妇女的随机样本记录。对青春期(10-14 岁、15-19 岁)和成年(≥20 岁)母亲所生新生儿的 LBW 进行多变量逻辑和线性回归分析,然后对正常妊娠的初产妇进行分析,调整新生儿性别、产前护理和母亲居住地的位置。共有 4384 名母亲有单胎活产,1501 名初产妇有正常妊娠。早、晚期青少年出生 LBW 婴儿的几率明显高于成年母亲(OR=2.28,95%CI:1.09,4.78;OR=1.67,95%CI:1.30,2.14)。对于正常妊娠的初产妇,只有早青春期是如此(OR=3.07,95%CI:1.09,8.61)。成人(3178.7 克)与所有青少年年龄组(10-14 岁:2848.9 克;15-19 岁:2998.3 克)和正常妊娠的初产妇(10-14 岁:2900.8 克;15-19 岁:3059.2 克;≥20 岁:3151.8 克)之间的平均出生体重存在显著差异。结果表明,青少年和成年母亲在新生儿出生体重方面存在重要差异,尤其是在早期青少年中。未来关于 LBW 及其他不良出生结局的研究应将早期青少年视为一个更高风险的单独亚组。

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