Conde-Agudelo Agustin, Belizán José M, Lammers Cristina
Department of Obstetrics and Gynecology, Fundacion Clinica Valle del Lili, Cali, Colombia.
Am J Obstet Gynecol. 2005 Feb;192(2):342-9. doi: 10.1016/j.ajog.2004.10.593.
This study was undertaken to determine whether adolescent pregnancy is associated with increased risks of adverse pregnancy outcomes.
We studied 854,377 Latin American women who were younger than 25 years during 1985 through 2003 using information recorded in the Perinatal Information System database of the Latin American Center for Perinatology and Human Development, Montevideo, Uruguay. Adjusted odds ratios were obtained through logistic regression analysis.
After an adjustment for 16 major confounding factors, adolescents aged 15 years or younger had higher risks for maternal death, early neonatal death, and anemia compared with women aged 20 to 24 years. Moreover, all age groups of adolescents had higher risks for postpartum hemorrhage, puerperal endometritis, operative vaginal delivery, episiotomy, low birth weight, preterm delivery, and small-for-gestational-age infants. All adolescent mothers had lower risks for cesarean delivery, third-trimester bleeding, and gestational diabetes.
In Latin America, adolescent pregnancy is independently associated with increased risks of adverse pregnancy outcomes.
本研究旨在确定青少年怀孕是否与不良妊娠结局风险增加有关。
我们利用乌拉圭蒙得维的亚拉丁美洲围产期学与人类发展中心围产期信息系统数据库中记录的信息,对1985年至2003年期间年龄小于25岁的854,377名拉丁美洲女性进行了研究。通过逻辑回归分析获得调整后的比值比。
在对16个主要混杂因素进行调整后,与20至24岁的女性相比,15岁及以下的青少年产妇死亡、早期新生儿死亡和贫血风险更高。此外,所有年龄段的青少年产后出血、产褥期子宫内膜炎、阴道助产、会阴切开术、低出生体重、早产和小于胎龄儿的风险都更高。所有青少年母亲剖宫产、孕晚期出血和妊娠期糖尿病的风险较低。
在拉丁美洲,青少年怀孕与不良妊娠结局风险增加独立相关。