Department of Preventive Dentistry, Periodontology and Cariology, University of Göttingen, Göttingen, Germany.
Int Endod J. 2010 Jun;43(6):519-27. doi: 10.1111/j.1365-2591.2010.01709.x.
To compare the efficacy of different solutions (1% sodium hypochlorite, 10% citric acid and 20% EDTA) in the removal of calcium hydroxide from root canals.
One hundred single-rooted maxillary incisors were prepared to size 50 and split longitudinally. Two standardized grooves were cut into the apical and coronal part of the root canal dentine and filled with calcium hydroxide. The reassembled teeth were irrigated with a syringe and a size 30 needle using the following irrigants: (i) 20% EDTA, (ii) 10% citric acid, (iii) 1% NaOCl, (iv) 10% citric acid + 1% NaOCl, (v) 20% EDTA + 1% NaOCl and (vi) water (control). Volume of irrigant was 20 mL in each group, and irrigation time was 5 min. Evaluation of cleanliness of the blinded specimens was performed by two calibrated observers under a microscope with 30x magnification using a four-grade scoring system as described by van der Sluis et al. (2007). Statistical evaluation was performed using a SAS-macro for non-parametric multifactorial analysis (P < 0.05).
The best results were found for irrigation with EDTA and citric acid, whereas NaOCl and water showed the least effect. The combinations of irrigants did not result in improvement in terms of cleanliness.
None of the irrigants nor their respective combinations were able to completely remove the calcium hydroxide. Chelating agents such as citric acid and EDTA showed the best results. The combination of chelators and NaOCl did not result in significant improvement of calcium hydroxide removal.
比较不同溶液(1%次氯酸钠、10%柠檬酸和 20% EDTA)在清除根管内氢氧化钙方面的效果。
将 100 颗上颌单根切牙预备至 50 号,并纵向劈开。在根管牙本质的根尖和冠部切两个标准化的凹槽,并填入氢氧化钙。用注射器和 30 号针头冲洗重新组装的牙齿,使用以下冲洗剂:(i)20%EDTA、(ii)10%柠檬酸、(iii)1%次氯酸钠、(iv)10%柠檬酸+1%次氯酸钠、(v)20%EDTA+1%次氯酸钠和(vi)水(对照)。每组冲洗剂的体积为 20 毫升,冲洗时间为 5 分钟。用 30 倍放大倍数的显微镜对盲样的清洁度进行评估,采用 van der Sluis 等人(2007 年)描述的四级评分系统由两名经过校准的观察者进行评估。使用非参数多因素分析的 SAS 宏(P<0.05)进行统计评估。
EDTA 和柠檬酸冲洗的效果最好,而次氯酸钠和水的效果最差。冲洗剂的组合并没有在清洁度方面得到改善。
没有一种冲洗剂或其组合能够完全清除氢氧化钙。螯合剂如柠檬酸和 EDTA 效果最好。螯合剂和次氯酸钠的组合并没有显著提高氢氧化钙的去除效果。