Department of Conservative Dentistry and Endodontics, Meenakshi Ammal Dental College and Hospital, Meenakshi Academy of Higher Education and Research (MAHER), Tamilnadu, India.
Department of Preventive and Restorative Dentistry, University of Sharjah, Sharjah, UAE.
Eur Endod J. 2022 Mar;7(1):11-19. doi: 10.14744/eej.2021.73644.
To identify whether root canal irrigants with calcium chelation ability play a role in the removal of calcium hydroxide (CH) from the root canals when compared to non-chelators.
The protocol is registered in the Open Science Framework registry (doi 10.17605/OSF.IO/CHG2Q). PubMed, Scopus, Embase, Cochrane Library, ProQuest, Google Scholar, Science direct and open grey databases were searched until March 2021. Laboratory studies comparing the effectiveness of calcium chelators in the removal of CH with non-chelators delivered using needle irrigation, irrigation agitation or instrumentation techniques were included. The quality of included studies was appraised using a modified Joanna Briggs Institute critical appraisal checklist for a randomised clinical trial. Two independent reviewers were involved in study selection, data extraction, appraising the quality of studies. Any disagreements were resolved by a third reviewer.
The current review included 17 studies, with 16 being of "moderate" quality and one of "low" quality. Due to methodological differences within the included studies, quantitative analysis was not performed. Laboratory studies were only included in the current review because no clinical study exists on this topic. Evidence from the review indicates that calcium chelators are superior to non-chelators in the removal of CH when used with needle irrigation, passive ultrasonic irrigation and instrumentation techniques.
Calcium chelators are superior in the removal of CH from the root canal system over non-chelators.
确定与非螯合剂相比，具有钙螯合能力的根管冲洗剂在去除根管内氢氧化钙 (CH) 时是否发挥作用。
该方案在开放科学框架注册（doi 10.17605/OSF.IO/CHG2Q）。检索了 PubMed、Scopus、Embase、Cochrane 图书馆、ProQuest、Google Scholar、Science direct 和开放灰色数据库，截至 2021 年 3 月。纳入了比较钙螯合剂与非螯合剂在使用针状冲洗、冲洗搅拌或器械技术输送时去除 CH 的效果的实验室研究。使用改良 Joanna Briggs 研究所随机临床试验批判性评价清单评估纳入研究的质量。两名独立评审员参与了研究选择、数据提取、评价研究质量。任何分歧均由第三名评审员解决。
目前的综述共纳入了 17 项研究，其中 16 项为“中度”质量，1 项为“低”质量。由于纳入研究内的方法学差异，未进行定量分析。由于在这个主题上没有临床研究，因此仅将实验室研究纳入本综述。综述中的证据表明，在使用针状冲洗、被动超声冲洗和器械技术时，钙螯合剂在去除 CH 方面优于非螯合剂。
与非螯合剂相比，钙螯合剂在去除根管系统中的 CH 方面更具优势。
