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甲状旁腺功能减退症患者发生系统性红斑狼疮:病例报告及文献复习。

Development of systemic lupus erythematosus in a patient with hypoparathyroidism: a case report and review of the literature.

机构信息

Rheumatic Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Int J Rheum Dis. 2010 May;13(2):175-9. doi: 10.1111/j.1756-185X.2010.01464.x.

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease in which organs undergo damage. Hypoparathyroidism is a rare disease, which presents in two forms: hereditary and acquired. Cases of hypoparathyroidism and SLE rarely co-exist. Only six cases have been reported; five of them first presented with lupus and then hypoparathyroidism or simultaneously. We present here developing lupus disease in a woman who had idiopathic hypoparathyroidism. According to increasing data about the autoimmune origin of idiopathic hypoparathyroidism, these case reports suggest that there may be an autoimmune process linking these diseases.

摘要

系统性红斑狼疮(SLE)是一种自身免疫性疾病,会导致器官受损。甲状旁腺功能减退症是一种罕见的疾病,有两种形式:遗传性和获得性。甲状旁腺功能减退症和 SLE 同时存在的情况很少见。仅有 6 例报告;其中 5 例最初表现为狼疮,然后出现甲状旁腺功能减退症或同时出现。我们在此报告了一例特发性甲状旁腺功能减退症女性中狼疮疾病的发展。根据关于特发性甲状旁腺功能减退症的自身免疫起源的越来越多的数据,这些病例报告表明,可能存在一种将这些疾病联系起来的自身免疫过程。

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