Proverbio D, Perego R, Spada E, Ferro E
Department of Veterinary Clinical Science, University of Milan, Milan, Italy.
J Small Anim Pract. 2010 Jul;51(7):370-4. doi: 10.1111/j.1748-5827.2010.00951.x. Epub 2010 Jun 9.
To determine the prevalence of adverse food reactions (AFRs) in dogs with dermatological signs presented to the referral dermatological clinic of the University of Milan.
The medical records of dogs with dermatological signs were reviewed. Prevalence of AFRs was calculated. Owner and clinician pruritus scores were compared. Breed, sex and age predisposition were statistically tested, as was the association between AFR and selected clinical features.
The prevalence of AFRs in dogs with dermatological signs was 12% (16 of 130). AFR was diagnosed in 26% of dogs with allergic disease and 48% of those subjected to a dietary trial. There was a significant association between AFRs and early onset of clinical signs (< 1 year) (OR=3.8; P=0.0221, 95% CI=1.27 to 11.16). There was a significant association between AFRs and both otitis externa (OR=5.9; P=0.0015, 95% CI=2 to 17.9) and perianal fistula (OR=26.1; P=0.0058, 95% CI=2.52 to 269.4), although all dogs with perianal fistulas were German shepherd dogs.
The prevalence of AFRs in the study population was higher than most reported values. Further studies are warranted to investigate the true prevalence of AFR and its possible association with perianal fistula and other potential markers.
确定前往米兰大学转诊皮肤科诊所就诊的有皮肤症状的犬只中食物不良反应（AFR）的患病率。
回顾有皮肤症状犬只的病历。计算AFR的患病率。比较主人和临床医生的瘙痒评分。对品种、性别和年龄易感性进行统计学检验，以及AFR与选定临床特征之间的关联。
有皮肤症状的犬只中AFR的患病率为12%（130只中有16只）。在26%的过敏性疾病犬只和48%进行饮食试验的犬只中诊断出AFR。AFR与临床症状早发（<1岁）之间存在显著关联（OR=3.8；P=0.0221，95%CI=1.27至11.16）。AFR与外耳道炎（OR=5.9；P=0.0015，95%CI=2至17.9）和肛周瘘管（OR=26.1；P=0.0058，95%CI=2.52至269.4）均存在显著关联，尽管所有患有肛周瘘管的犬只都是德国牧羊犬。
研究人群中AFR的患病率高于大多数报告值。有必要进一步研究以调查AFR的真实患病率及其与肛周瘘管和其他潜在标志物的可能关联。
