Division of Plastic Surgery, Department of Surgery, University of Washington, Seattle, WA 98104, USA.
Burns. 2010 Nov;36(7):975-83. doi: 10.1016/j.burns.2010.04.014. Epub 2010 Jul 1.
Pressure garment therapy is standard of care for prevention and treatment of hypertrophic scarring after burn injury. Nevertheless there is little objective data that confirms effectiveness. The purpose of this study was to determine the effectiveness of pressure garment therapy with objective data obtained with a randomized within-wound comparison. We enrolled consecutive patients with forearm injuries over a 12-year period. The subjects wore custom garments with normal and low compression randomized to either the proximal or distal zones. Hardness, color and thickness of wounds were objectively measured using appropriate devices; clinical appearance was measured by a panel masked to the identity of the pressure treated area. Wounds treated with normal compression were significantly softer, thinner, and had improved clinical appearance. There was no interaction of any effect with patient ethnicity. However, these findings were clinically evident only with moderate to severe scarring. We conclude that pressure garment therapy is effective, but that the clinical benefit is restricted to those patients with moderate or severe scarring.
压力衣治疗是烧伤后预防和治疗增生性瘢痕的标准治疗方法。然而，几乎没有客观数据证实其有效性。本研究的目的是通过随机的伤口内比较，用客观数据确定压力衣治疗的效果。我们在 12 年期间连续招募了前臂受伤的患者。这些患者穿着定制的压力衣，压力值有正常和低两种，压力衣随机分配到近端或远端区域。使用适当的设备客观测量伤口的硬度、颜色和厚度；通过对压力治疗区域的身份进行盲法评估来测量临床外观。正常压力组的伤口明显更柔软、更薄，且临床外观改善。患者种族对任何效果均无交互作用。然而，只有在中重度瘢痕的情况下，这些发现才具有明显的临床意义。我们的结论是，压力衣治疗是有效的，但临床获益仅限于中重度瘢痕的患者。
