Department of Oral and Maxillofacial Surgery, King Abdulaziz University, Jeddah, Saudi Arabia.
Int J Oral Maxillofac Surg. 2010 Sep;39(9):933-6. doi: 10.1016/j.ijom.2010.04.042.
A rare case of syngnathia (maxillomandibular fusion) is described in a 2-year-old boy who presented from a rural area of Saudi Arabia. The child had the problem since birth and had undergone two surgical attempts to release the fusion at another institution but both had failed and recurrence occurred. In the authors' institute, the patient underwent two separate surgical procedures at the age of 2 and 3 years. Both procedures were followed by a period of aggressive physiotherapy, but the patient presented with re-fusion of the mandible and the maxilla 1 year after the first operation and 5 months after the second operation. It was decided to defer treatment until puberty. The cause of the relapse may be the high osteogenic potential because of his youth or the failure of the parents to maintain the active physiotherapy protocol because they live in a rural area and close follow-up was difficult. A possible genetic predisposition for bone formation at this site should be investigated.
描述了一例罕见的颌间融合（上颌骨与下颌骨融合）病例，患者为一名 2 岁男孩，来自沙特阿拉伯的农村地区。患儿自出生起就存在该问题，并在另一家机构接受了两次试图释放融合的手术，但均失败且复发。在作者所在机构，患儿在 2 岁和 3 岁时分别接受了两次单独的手术。两次手术后都进行了积极的物理治疗，但在第一次手术后 1 年和第二次手术后 5 个月，患者出现了下颌骨和上颌骨再次融合。决定推迟到青春期再进行治疗。复发的原因可能是由于患儿年轻，骨生成潜力高，或者父母未能坚持积极的物理治疗方案，因为他们生活在农村地区，难以进行密切随访。应该调查该部位骨形成的可能遗传倾向。
