Department of Oral and Maxillofacial Surgery, S.D.M. College of Dental Sciences and Hospital, Sattur, Dharwad, Karnataka, India.
Int J Oral Maxillofac Surg. 2010 Oct;39(10):1036-9. doi: 10.1016/j.ijom.2010.04.040.
Plasmablastic lymphoma (PBL) is a diffuse large B-cell lymphoma, a new entity, the incidence of which is increasing, predominantly in the oral cavity of immunocompromised patients, most of whom are infected with human immunodeficiency virus (HIV); only four cases have been reported in non-HIV-infected patients. This report details two cases of PBL of the oral cavity in immunocompetent patients. In both cases, the tumour manifested as a solitary, firm mandibular swelling with dense infiltration of plasma and blastoid cells in the stroma with strong positivity for CD 138 and negativity for CD 20. The patients received radiotherapy and chemotherapy, which resulted in complete remission of the lesion. This is the only case report of two cases of PBL in the oral cavity in immunocompetent patients in which both patients received treatment and showed complete remission of the lesion.
浆母细胞淋巴瘤（PBL）是一种弥漫性大 B 细胞淋巴瘤，是一种新的实体瘤，其发病率正在增加，主要发生在免疫功能低下患者的口腔，其中大多数患者感染了人类免疫缺陷病毒（HIV）；仅有四例报告发生在未感染 HIV 的患者中。本报告详细介绍了两例免疫功能正常患者的口腔 PBL。在这两种情况下，肿瘤表现为单一、坚硬的下颌肿胀，基质中存在密集的浆细胞和母细胞浸润，CD138 强阳性，CD20 阴性。患者接受了放疗和化疗，病变完全缓解。这是两例免疫功能正常患者口腔 PBL 的唯一病例报告，两例患者均接受了治疗，病变完全缓解。
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