卡马西平在一名患有严重血清病的患者中诱导产生抗卡马西平抗体。
Anticarbamazepine antibody induced by carbamazepine in a patient with severe serum sickness.
作者信息
Hosoda N, Sunaoshi W, Shirai H, Bando Y, Miura H, Igarashi M
机构信息
Department of Paediatrics, Kitasato University School of Medicine, Kanagawa, Japan.
出版信息
Arch Dis Child. 1991 Jun;66(6):722-3. doi: 10.1136/adc.66.6.722.
Abstract
Anticarbamazepine antibody was detected in a patient who had clinical signs of serum sickness induced by carbamazepine. Skin rash, fever, oedema, and lymphadenopathy are classic signs of severe adverse reaction, but although immunological hypersensitivity is thought to be a contributory factor, the presence of anticarbamazepine antibody has not previously been reported to our knowledge.
摘要
在一名有卡马西平所致血清病临床症状的患者中检测到了抗卡马西平抗体。皮疹、发热、水肿和淋巴结病是严重不良反应的典型症状，尽管免疫超敏反应被认为是一个促成因素，但据我们所知，此前尚未有抗卡马西平抗体存在的报道。
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Allergic reactions to drugs and biologic agents.对药物和生物制剂的过敏反应。
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Metabolism and Pharmacolinetics of Carbamazepine.卡马西平的代谢与药代动力学
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Deposits of plasma proteins in the skin during treatment with carbamazepine and diphenylhydantoin.在使用卡马西平和苯妥英治疗期间皮肤中血浆蛋白的沉积。
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