Araki H, Kano S, Nishima S, Ogasawara M, Matsuzaki M, Tanaka M M, Tanaka H, Shindou M
Division of Pediatrics, National Minami Fukuoka Chest Hospital.
Arerugi. 1991 Mar;40(3 Pt 1):205-14.
Twelve children with exercise-induced bronchospasm (EIB) participated in our physical training program to determine whether it improves physical working capacity and EIB. The effect of physical training on the bronchial reactivity to inhaled 3.6% NaCl was also investigated. The training was performed by bicycle ergometer for four weeks every day at 125% of WBPLA1 (work load at first breaking point of lactic acid). The results obtained were as follows. 1. Heart rate decreased from 188.5 +/- 9.6 bpm before to 178.4 +/- 9.7 bpm after training at 150% of WBPLA1 (p less than 0.05). After training at 175% of WBPLA1 it decreased also from 174.0 +/- 11.9 bpm to 165.6 +/- 11.3 bpm. Maximum oxygen consumption increased from 34.5 +/- 3.5 ml/min/kg to 41.4 +/- 4.0 ml/min/kg after training (p less than 0.001). 2. Max. % fall in FEV1.0 decreased from 27.1 +/- 24.0% before to 18.0 +/- 17.1% after training at 150% of WBPLA1 (p less than 0.05). After training at 175% of WBPLA1 it decreased also from 37.4 +/- 17.4% to 30.0 +/- 22.1%. 3. The mean dose of inhaled 3.6% NaCl inducing 20% fall in FEV1.0 (PD20) was 4.2 +/- 5.9 ml before training. The PD20 was significantly higher after training (8.6 +/- 4.0 ml). There was no significant change in PD20 in the control group. Based on these results, it was concluded that physical training increased physical working capacity and improved EIB and bronchial hyperreactivity to inhaled 3.6% NaCl in asthmatic children.
12名运动诱发性支气管痉挛(EIB)患儿参加了我们的体能训练项目,以确定该训练是否能提高体能以及改善EIB。同时还研究了体能训练对支气管对吸入3.6%氯化钠反应性的影响。训练通过自行车测力计进行,为期四周,每天以无氧阈第一拐点时工作负荷(WBPLA1)的125%进行。获得的结果如下。1. 在WBPLA1的150%负荷下训练后,心率从训练前的188.5±9.6次/分钟降至178.4±9.7次/分钟(p<0.05)。在WBPLA1的175%负荷下训练后,心率也从174.0±11.9次/分钟降至165.6±11.3次/分钟。最大耗氧量在训练后从34.5±3.5毫升/分钟/千克增加到41.4±4.0毫升/分钟/千克(p<0.001)。2. 在WBPLA1的150%负荷下训练后,第一秒用力呼气容积(FEV1.0)的最大下降百分比从训练前的27.1±24.0%降至18.0±17.1%(p<0.05)。在WBPLA1的175%负荷下训练后,该百分比也从37.4±17.4%降至30.0±22.1%。3. 训练前,使FEV1.0下降20%的吸入3.6%氯化钠的平均剂量(PD20)为4.2±5.9毫升。训练后PD20显著升高(8.6±4.0毫升)。对照组的PD20无显著变化。基于这些结果,得出结论:体能训练提高了哮喘患儿的体能,改善了EIB以及支气管对吸入3.6%氯化钠的高反应性。