Bobrik I I, Davidenko L M
Arkh Anat Gistol Embriol. 1991 Feb;100(2):42-8.
Time of appearance, succession and ultrastructural peculiarities of pancreatic endocrinocytes have been studied in human embryogenesis. A-insulocytes (the 7th-8th week) appear before B-endocrinocytes (the 9th-10th week). Before the 10th week A-insulocytes possess a higher degree of cytodifferentiation and development of the mechanisms necessary for hormones secretion. This should be taken into account at allotransplantation of the embryonal pancreas with the aim to correct insulin insufficiency.
在人类胚胎发育过程中,对胰腺内分泌细胞的出现时间、演替过程及超微结构特征进行了研究。A胰岛细胞(第7 - 8周)比B内分泌细胞(第9 - 10周)出现得早。在第10周之前,A胰岛细胞具有更高程度的细胞分化以及激素分泌所需机制的发育。在进行胚胎胰腺同种异体移植以纠正胰岛素不足时,应考虑到这一点。