Lutz H, Heppt W, Hittel J P, Adler D
Univ.-HNO-Klinik Heidelberg.
Laryngorhinootologie. 1991 Apr;70(4):187-90. doi: 10.1055/s-2007-998018.
In 196 patients suffering from disease of the cephalic salivary glands and in 57 healthy controls the concentration of albumin in parotid and submandibular saliva was measured by the immunodiffusion technique. To summarize the results, albumin seems to be a reliable marker of inflammations of the salivary glands even in the early stages and is therefore recommended for the primary diagnostic and the follow-up of acute and chronic inflammatory conditions of the major cephalic salivary glands. In combination with the evaluation of the flow rate, other sialochemic parameters like phosphohexose isomerase and kallikrein activity, B-mode sonography and fine needle aspiration biopsy the frequency of x-ray examination of the radiosensitive salivary glands may be reduced.
对196例患有头面部唾液腺疾病的患者以及57名健康对照者,采用免疫扩散技术测定腮腺和颌下腺唾液中的白蛋白浓度。总结结果可知,白蛋白似乎是唾液腺炎症的可靠标志物,即使在早期阶段也是如此,因此推荐将其用于主要头面部唾液腺急慢性炎症的初步诊断及随访。结合唾液流速评估、其他唾液化学参数(如磷酸己糖异构酶和激肽释放酶活性)、B型超声检查以及细针穿刺活检,可减少对放射性敏感唾液腺进行X线检查的频率。