EaStCHEM School of Chemistry, University of St Andrews, St. Andrews KY16 9ST, UK.
J Am Chem Soc. 2010 Jul 7;132(26):8858-9. doi: 10.1021/ja103429q.
A highly efficient [(NHC)Au(I)]-based (NHC = N-heterocyclic carbene) catalytic system for the carboxylation of aromatic and heteroaromatic C-H bonds was developed. The significant base strength of the Au-OH species is at the origin of the activation process and permits the facile functionalization of C-H bonds without the use of other organometallic reagents.
发展了一种高效的基于[(NHC)Au(I)]的（NHC = 氮杂环卡宾）催化体系，用于芳基和杂芳基 C-H 键的羧化反应。Au-OH 物种的强碱性是活化过程的起源，并允许在不使用其他有机金属试剂的情况下轻松实现 C-H 键的功能化。
