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Polymorphism of human CYP2D genes involved in drug metabolism: possible relationship to individual cancer risk.

作者信息

Nebert D W

机构信息

Department of Environmental Health, University of Cincinnati Medical Center, Ohio 45267-0056.

出版信息

Cancer Cells. 1991 Mar;3(3):93-6.

PMID:2054261
Abstract
摘要

相似文献

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Polymorphism of human CYP2D genes involved in drug metabolism: possible relationship to individual cancer risk.
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Genetic polymorphism of enzymes involved in xenobiotic metabolism and the risk of lung cancer.遗传多态性的酶参与异生物代谢和肺癌的风险。
Environ Health Prev Med. 2002 May;7(2):47-59. doi: 10.1007/BF02897330.
2
Human variability and susceptibility to trichloroethylene.人类对三氯乙烯的变异性和易感性。
Environ Health Perspect. 2000 May;108 Suppl 2(Suppl 2):201-14. doi: 10.1289/ehp.00108s2201.
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The sparteine/debrisoquine (CYP2D6) oxidation polymorphism and the risk of lung cancer: a meta-analysis.
Eur J Clin Pharmacol. 1997;51(5):389-93. doi: 10.1007/s002280050219.
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Statistical models for genetic susceptibility in toxicological and epidemiological investigations.毒理学和流行病学调查中遗传易感性的统计模型。
Environ Health Perspect. 1994 Jan;102 Suppl 1(Suppl 1):77-82. doi: 10.1289/ehp.94102s177.
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Prediction of phenotype for acetylation and for debrisoquine hydroxylation by DNA-tests in healthy human volunteers.
Eur J Clin Pharmacol. 1992;43(4):399-403. doi: 10.1007/BF02220616.