孕妇吸烟与前置胎盘

Maternal smoking and placenta previa.

作者信息

Kramer M D, Taylor V, Hickok D E, Daling J R, Vaughan T L, Hollenbach K A

机构信息

Department of Epidemiology, University of Washington, Seattle.

出版信息

Epidemiology. 1991 May;2(3):221-3. doi: 10.1097/00001648-199105000-00012.

DOI:10.1097/00001648-199105000-00012

PMID:2054407

Abstract

We conducted a case-control study of the relation between smoking and placenta previa, using Washington State birth certificate data from 1984 through 1987. The study population was comprised of live, singleton births to women whose pregnancies were complicated by placenta previa (N = 598) and randomly selected controls (N = 2,422) from the same time period. We used logistic regression to estimate odds ratios (OR) and their 95% confidence intervals (CI). Maternal smoking approximately doubled the risk of placenta previa after adjustment for the confounding effect of maternal age (OR = 2.1, 95% CI: 1.7-2.5).

摘要

我们利用1984年至1987年华盛顿州出生证明数据，开展了一项关于吸烟与前置胎盘关系的病例对照研究。研究人群包括妊娠合并前置胎盘的活产单胎产妇（N = 598）以及同期随机选取的对照组（N = 2422）。我们采用逻辑回归来估计比值比（OR）及其95%置信区间（CI）。在对产妇年龄的混杂效应进行调整后，产妇吸烟使前置胎盘风险增加了约一倍（OR = 2.1，95% CI：1.7 - 2.5）。