Taylor V M, Peacock S, Kramer M D, Vaughan T L
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Obstet Gynecol. 1995 Nov;86(5):805-8. doi: 10.1016/0029-7844(95)00262-P.
To investigate the frequency of placenta previa among Asian women.
We conducted a population-based case-control study using Washington state birth certificate data from 1984-1987. Our study population included 810 women with pregnancies complicated by placenta previa and 2917 randomly selected controls. Unconditional logistic regression was used to estimate odds ratios (OR) and their 95% confidence intervals (CI), and interaction terms were used to examine effect modification. Potential confounding by maternal age, gravidity and parity, maternal smoking during pregnancy, and a history of abortion or cesarean delivery was adjusted for in the analysis.
The frequency of placenta previa during the study period was 3.3 per 1000 live births. Women of Asian origin were 86% more likely (OR 1.86, 95% CI 1.38-2.51) to have a delivery complicated by placenta previa than were white women. This association was stronger among women without a previous live birth (OR 2.51, 95% CI 1.57-4.01) than those who previously had experienced a live birth (OR 1.50, 95% CI 1.01-2.25).
Asian women residing in the United States are at increased risk of placenta previa. If confirmed by others, our results suggest that obstetricians should consider meticulous ultrasound evaluations during pregnancy to rule out the presence of placenta previa in Asian-American women.
调查亚洲女性前置胎盘的发生率。
我们利用华盛顿州1984 - 1987年的出生证明数据进行了一项基于人群的病例对照研究。我们的研究人群包括810例妊娠合并前置胎盘的女性和2917例随机选取的对照。采用无条件逻辑回归估计比值比（OR）及其95%置信区间（CI），并使用交互项检验效应修正。分析中对产妇年龄、孕次和产次、孕期吸烟以及流产或剖宫产史等潜在混杂因素进行了校正。
研究期间前置胎盘的发生率为每1000例活产3.3例。亚裔女性分娩合并前置胎盘的可能性比白人女性高86%（OR 1.86，95% CI 1.38 - 2.51）。这种关联在既往无活产史的女性中（OR 2.51，95% CI 1.57 - 4.01）比既往有活产史的女性中（OR 1.50，95% CI 1.01 - 2.25）更强。
居住在美国的亚洲女性前置胎盘风险增加。如果其他人的研究证实了我们的结果，这表明产科医生在孕期应考虑进行细致的超声评估，以排除亚裔美国女性前置胎盘的存在。
