Department of Neurobiology, Care Sciences and Society (NVS), Division of neurorehabilitation, Karolinska Institutet, 139 89 Stockholm, Sweden.
J Rehabil Med. 2010 May;42(5):489-92. doi: 10.2340/16501977-0541.
Comparison of prevalence of cardiovascular disease risks in persons with chronic traumatic paraplegia with those in the general population.
Cross-sectional comparative study.
A total of 135 individuals, age range 18-79 years, with chronic (> or = 1 year) traumatic paraplegia.
The prevalences of diabetes mellitus, dyslipidaemia, hypertension, overweight, and smoking, were assessed in the study population and were compared with an age- and gender-matched sample of the general population in the region under study. History of myocardial infarction and medication for dyslipidaemia, hypertension, and diabetes mellitus were also recorded. chi2 tests were used to compare the paraplegic cohort with the general population sample.
Significantly more persons with paraplegia reported a history of myocardial infarction (5.9%) than those in the comparison group (0.7%). The prevalences of diabetes mellitus (5.9%), dyslipidaemia (11.1%), and hypertension (14.1%) were also significantly higher in the paraplegic group, as were drug treatment for these disorders.
Persons with paraplegia report increased prevalences of diabetes mellitus, hypertension, and dyslipidaemia, in particular, compared with the general population. Population-based screening and therapeutic counter-measures for these conditions may therefore be particularly indicated for this patient group.
比较慢性创伤性截瘫患者与普通人群中心血管疾病风险的患病率。
横断面对比研究。
共 135 名年龄在 18-79 岁之间、患有慢性（>或=1 年）创伤性截瘫的患者。
评估研究人群中糖尿病、血脂异常、高血压、超重和吸烟的患病率，并将其与研究地区年龄和性别匹配的一般人群样本进行比较。还记录了心肌梗死病史和血脂异常、高血压和糖尿病的药物治疗情况。使用 chi2 检验比较截瘫组与一般人群样本。
截瘫患者报告心肌梗死病史（5.9%）的人数明显多于对照组（0.7%）。截瘫组的糖尿病（5.9%）、血脂异常（11.1%）和高血压（14.1%）的患病率也明显更高，这些疾病的药物治疗也更多。
与普通人群相比，截瘫患者报告糖尿病、高血压和血脂异常的患病率更高。因此，针对这些疾病的基于人群的筛查和治疗措施可能特别适用于该患者群体。
