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[The effect of bone marrow transplantation on the dynamic recovery of the morphofunctional properties of the pancreas in irradiated recipients].

作者信息

Tsutsaeva A A, Glushko T A, Shatilova L E, Tupchienko G S

出版信息

Biull Eksp Biol Med. 1991 Mar;111(3):318-20.

PMID:2054516
Abstract

Effect of transplantation of syngeneic bone marrow in the dose of 1 X 10(7) cell/ml on the state of pancreatic gland in lethally irradiated recipients has been studied at different stages of posttransplantation period for 3 months using 250 linear male rats G (CBA x C57B). Histological and biochemical investigation, conducted in dynamics, have shown that transplantation of native and cryopreserved bone marrow to lethally irradiated animals facilitates activation of compensatory-restoration processes manifesting themselves in mitotic division of glandular and epithelial cells, as well as optimizes exchange of carbohydrates in the irradiated organism.

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