Lodha Ankur, Haran Mehandi, Shetty Vijay, Sadiq Adnan, Hollander Gerald, Shani Jacob
Maimonides Medical Center, Brooklyn, New York, USA.
Echocardiography. 2010 Jul;27(6):E57-9. doi: 10.1111/j.1540-8175.2009.01144.x. Epub 2010 Jun 9.
Hypereosinophilic syndrome is a rare condition characterized by idiopathic eosinophilia with organ system involvement. Cardiac involvement portends a less favorable prognosis as it can be complicated by development of heart failure, valvular dysfunction, and restrictive cardiomyopathy. We present a rare case of hypereosinophilic syndrome with FIP1L1/PDGFRA fusion in a 50-year-old male associated with thrombus in left and right ventricle.
高嗜酸性粒细胞综合征是一种罕见疾病，其特征为特发性嗜酸性粒细胞增多并累及器官系统。心脏受累预示预后较差，因为可能并发心力衰竭、瓣膜功能障碍和限制性心肌病。我们报告一例50岁男性罕见的高嗜酸性粒细胞综合征病例，该患者存在FIP1L1/PDGFRA融合基因，且左右心室均有血栓形成。
