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表现为双心室心脏血栓的嗜酸性粒细胞增多综合征

Hypereosinophilic syndrome presenting with biventricular cardiac thrombi.

作者信息

Lodha Ankur, Haran Mehandi, Shetty Vijay, Sadiq Adnan, Hollander Gerald, Shani Jacob

机构信息

Maimonides Medical Center, Brooklyn, New York, USA.

出版信息

Echocardiography. 2010 Jul;27(6):E57-9. doi: 10.1111/j.1540-8175.2009.01144.x. Epub 2010 Jun 9.

Abstract

Hypereosinophilic syndrome is a rare condition characterized by idiopathic eosinophilia with organ system involvement. Cardiac involvement portends a less favorable prognosis as it can be complicated by development of heart failure, valvular dysfunction, and restrictive cardiomyopathy. We present a rare case of hypereosinophilic syndrome with FIP1L1/PDGFRA fusion in a 50-year-old male associated with thrombus in left and right ventricle.

摘要

高嗜酸性粒细胞综合征是一种罕见疾病,其特征为特发性嗜酸性粒细胞增多并累及器官系统。心脏受累预示预后较差,因为可能并发心力衰竭、瓣膜功能障碍和限制性心肌病。我们报告一例50岁男性罕见的高嗜酸性粒细胞综合征病例,该患者存在FIP1L1/PDGFRA融合基因,且左右心室均有血栓形成。

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