Dipartimento Clinico-Sperimentale di Medicina e Farmacologia. Policlinico G. Martino Università di Messina, Italy.
J Cardiovasc Med (Hagerstown). 2010 Apr;11(4):322-4. doi: 10.2459/JCM.0b013e328330c5ac.
We present a case of Loëffler endocarditis in a 45-year-old man. This syndrome is characterized by unexplained prolonged and marked hypereosinophilia (>1500 eosinophils/mm), absence of a primary cause of hypereosinophilia and evidence of eosinophil-mediated organ damage. Detection of cardiac damage is based on electrocardiography, echocardiography, cardiac MRI and endomyocardial biopsy. Two-dimensional echocardiography is an essential tool for diagnosis. In this case, a transthoracic echocardiogram revealed a complete obliteration of the apex of both ventricles associated with a restrictive left ventricular filling pattern.
我们报告 1 例 45 岁男性的 Löeffler 心内膜炎。该综合征的特征为不明原因的持续性、显著的嗜酸性粒细胞增多症（>1500 个嗜酸性粒细胞/mm），无嗜酸性粒细胞增多症的原发性病因和嗜酸性粒细胞介导的器官损伤证据。心脏损伤的检测基于心电图、超声心动图、心脏 MRI 和心内膜心肌活检。二维超声心动图是诊断的基本工具。在本例中，经胸超声心动图显示左右心室心尖完全闭塞，左心室充盈模式呈限制性。
