Department of Ophthalmology, Gachon University, Gil Hospital, Incheon, Korea.
Acta Ophthalmol. 2010 May;88(3):e73-7. doi: 10.1111/j.1755-3768.2010.01873.x.
To evaluate the efficacy of the fluorescein dye disappearance test (FDDT) and measurement of tear meniscus height (TMH) in the diagnosis and postoperative assessment of nasolacrimal duct obstruction (NLDO).
The study group included 42 eyes of 42 patients who had a diagnosis of primary acquired nasolacrimal duct obstruction (PANDO) or functional nasolacrimal duct obstruction (FNDO) and underwent endoscopic transnasal dacryocystorhinostomy. The control group included 38 eyes of 38 people without tearing. The values of the FDDT, TMH and tearing symptom score (TSS), which was evaluated in five levels based on patients' history taking, were measured before surgery, and 1 day, 2 weeks, 1, 3 and 6 months after surgery. The values of the FDDT, TMH and TSS in the study group were compared with those of the control group.
The preoperative values of the FDDT, TMH and TSS were 0.7 +/- 0.4, 0.22 +/- 0.08 mm and 1.6, respectively, in the control group and 3.0 +/- 0.8, 0.53 +/- 0.15 mm and 4.4, respectively, in the study group. These differences were statistically significant. Also, at each follow-up, the postoperative values of the FDDT and TMH decreased significantly compared to their preoperative values in the study group. The postoperative TSS decreased significantly compared to the preoperative values at each follow-up except at postoperative 1-day follow-up. There were no significant differences in the preoperative values of the FDDT, TMH and TSS between the types of NLDO. The TSS had positive correlations with the FDDT and TMH before and after surgery.
These results suggest that the FDDT and TMH measurement might be effective in the diagnosis and postoperative assessment of NLDO.
评估荧光素染料消失试验(FDDT)和泪膜高度(TMH)测量在鼻泪管阻塞(NLDO)的诊断和术后评估中的疗效。
研究组包括 42 例原发性获得性鼻泪管阻塞(PANDO)或功能性鼻泪管阻塞(FNDO)患者的 42 只眼,行内镜经鼻泪囊吻合术。对照组包括 38 名无流泪者的 38 只眼。在术前、术后 1 天、2 周、1、3 和 6 个月测量 FDDT、TMH 和流泪症状评分(TSS),根据患者的病史评估 TSS 分为 5 个等级。比较研究组和对照组的 FDDT、TMH 和 TSS 值。
对照组术前 FDDT、TMH 和 TSS 值分别为 0.7±0.4、0.22±0.08mm 和 1.6,研究组分别为 3.0±0.8、0.53±0.15mm 和 4.4,差异有统计学意义。而且,在每个随访时,研究组的术后 FDDT 和 TMH 值均较术前显著降低。除术后 1 天随访外,在每个随访时,术后 TSS 均较术前显著降低。NLDO 类型术前 FDDT、TMH 和 TSS 值差异无统计学意义。术前和术后 TSS 与 FDDT 和 TMH 呈正相关。
这些结果表明,FDDT 和 TMH 测量可能有助于 NLDO 的诊断和术后评估。